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  • Electronic Resource  (2)
  • Fitness  (1)
  • Imipramine  (1)
Material
  • Electronic Resource  (2)
Years
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 21 (1971), S. 101-110 
    ISSN: 1432-2072
    Keywords: Sleep ; Noradrenaline ; Debrisoquine ; Overdose ; Guanethidine ; Propranolol ; β-Blockers ; Isoprenaline ; Dexamphetamine ; Imipramine ; MAOI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Debrisoquine in dosage of 20–60 mg continued for up to 10 days caused suppression of human paradoxical sleep and withdrawal rebound, and also increased intra-sleep restlessness. An overdose of debrisoquine 200 mg caused suppression of paradoxical sleep and a rebound of over 2 weeks duration. Guanethidine 20–40 mg for 21 days did not affect paradoxical sleep but increased intra-sleep restlessness and reduced stages 3 + 4 sleep. Propranolol 120 mg had no discernable effect on sleep and did not prevent actions of dexamphetamine sulphate 10 mg nor of imipramine 75 mg. The findings relate to theories of cerebral noradrenaline in the control of sleep mechanisms.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 53 (1984), S. 1-4 
    ISSN: 1439-6327
    Keywords: Fitness ; Exercise ; Sleep ; Training ; Restorative
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Eight army recruits were studied at the start, middle, and end of their initial 18-week training programme. At each point the subjects were studied for four consecutive nights in the sleep laboratory. Their sleep was characterized by the means of the recordings on the last two nights. Within 2 days of the sleep recordings (but never on the same day) each subject spent 2 non-consecutive days in the exercise laboratory. On the 1st day a maximum oxygen consumpton ( $$\dot V_{{\text{O}}_{\text{2}} }$$ max) measurement was performed on a treadmill and on the 2nd day a 24-min progressive exercise bicycle ergometer test was carried out with simultaneous venous sampling (for lactic acid measurements) and oxygen consumption recordings from which the lactate turn point (LTP) was calculated. LTP was used as a measure of fitness. Approximately 1 week after the above measures lean muscle mass as calculated by total body potassium estimation was obtained for each subject. Slow wave sleep (SWS) as a percentage of total sleep time increased significantly between the start and the measurements at 9 and 18 weeks, being 21.9%, 29.9%, and 28.5% respectively. Anaerobic threshold increased significantly (P〈0.05) over the first 9 weeks and continued to increase to the end of the training period (P〈0.001) using $$\dot V_{{\text{O}}_{\text{2}} }$$ when lactate level was 2 mmol/l as a percentage of $$\dot V_{{\text{O}}_{\text{2}} }$$ max. With increase in fitness, sleep onset latency and wake time during sleep decreased and sleep efficiency improved. The results suggest that as fitness increases sleep quality improves.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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