ISSN:
1432-1076
Keywords:
Newborn infants
;
Glucose homeostasis
;
Medium chain triglycerides
;
Ketogenesis
;
Hypoglycaemia
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The effect of oral lipid supplementation (2.9 g/day containing 67% medium chain triglycerides) on the prevention of neonatal hypoglycaemia was evaluated in 28 low birth weight infants (mean±1 SD for gestational age: 36±1.2 weeks and birth weight: 1778±230 g) and compared to a control group of 23 infants with similar gestational age, birth weight and sex. The incidence of hypoglycaemic patients with plasma glucose 〈1.72 mmol/l was 8/23 (35%) in the control group versus 2/28 (7%) in the supplemented group: χ2=6.72; P〈0.01. Determinations of plasma beta-hydroxybutyrate concentrations in 11 infants of the supplemented group did not show values higher than 1.2 mmol/l. This prospective study shows that supplementation with lipids can prevent the occurrence of hypoglycaemia in low birth weight infants.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00442214
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