ISSN:
1433-0350
Keywords:
Hydrocephalus
;
Shunt malfunction
;
Hypoxia
;
Hypoxanthine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We used high performance liquid chromatography to determine the concentration of purine metabolites in the cerebrospinal fluid of three hydrocephalic children with a history of shunt malfunction. Hypoxanthine and xanthine levels were high in comparison with controls. We consider these purines to be valuable indicators of disturbance of neuronal metabolism following the sustained rise in intracranial pressure caused by shunt valve malfunction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00306272
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