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  • Electronic Resource  (2)
  • Keywords: HIV vaccines; HIV antibodies; gp120; gp41; Pepscan; statistical data analysis  (1)
  • traditional practice  (1)
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  • Electronic Resource  (2)
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  • 1
    ISSN: 1476-5535
    Keywords: Keywords: HIV vaccines; HIV antibodies; gp120; gp41; Pepscan; statistical data analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: To enhance utility of the linear epitope mapping (Pepscan) technique for assay of humoral responses linked to vaccination, two modifications were tested. First, peptides were incubated with serum contained in baths rather than individual wells. Second, a rigorous statistical model was developed to determine which peptide/antibody-binding interactions were significant. The modifications increased the ability to detect signal in these experiments by 15- to 45-fold. These two modifications were applied to linear epitope mapping of HIV seropositive volunteers under treatment with recombinant HIV gp160 and also to rabbits immunized with the same product. Changes in fine specificity of response were observed in animal models and human vaccine recipients over the course of an immunization series with this antigen.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Agroforestry systems 39 (1997), S. 205-210 
    ISSN: 1572-9680
    Keywords: fruit trees ; gender ; length of residence ; traditional practice
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract Tree holdings at homesteads and in homefields were investigated for two villages in Zimbabwe. Of the households, 90% owned at least one exotic tree. Trees were concentrated at homesteads and conserved indigenous trees tended to be edible fruit trees. Female heads of households (divorcees and widows) had fewer trees than households headed by men. Households with longer period of residence at a site had increased the proportion of indigenous fruit trees compared to non-fruit trees. Wealth status showed no relationship to tree holdings. The considerable tree planting and tree conservation activity around homesteads and in homefields has the effect of replacing non-fruit indigenous trees with exotic and indigenous fruit trees. Agroforestry research, extension and development should focus more on current practices, concentrate more on trees that farmers favour (such as fruit trees) and take into account differences among households.
    Type of Medium: Electronic Resource
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