ISSN:
1432-2072
Keywords:
Lithium
;
Rubidium
;
2-Oxoglutarate
;
Tricarboxylic acid cycle
;
Renal transport
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Lithium salts administered in therapeutic doses to four subjects who were kept on controlled diets increased up to fivefold the urinary output of some dicarboxylic acids. Some of the acids affected are intermediates in the tricarboxylic acid cycle, others are chemically similar but not directly related in metabolic terms. This is probably a direct effect on renal transport. Rubidium salts increased urinary 2-oxoglutarate output and blood 2-oxoglutarate levels, probably by some action on intermediary metabolism.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00491984
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