ISSN:
1432-0878
Keywords:
ACTH cells
;
Salmo gairdneri
;
Secretory products
;
Release in vitro
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary During organ culture of the pituitary of Salmo gairdneri, the secretory granules of the ACTH cell migrate to the distal pole of the cell where they persist even over prolonged periods of culture. Electron microscope studies suggest that the granule contents are released from the cell and that the accumulated material is extracellular. Immunofluorescent studies demonstrate immunoreactive ACTH within the cell cytoplasm but none or little associated with the accumulated extracellular material. A dissociation between ACTH and the granule “matrix” at about the time of granule release is proposed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00222993
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