ISSN:
1420-9071
Keywords:
Rat
;
embryo
;
embryo
;
rat
;
β-hydroxybutyrate
;
diabetes
;
maternal
;
fetal malformation
;
malformation
;
fetal
;
ketone bodies
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary In order to investigate further the relationship between maternal diabetes and fetal malformation, rat embryos were grown in vitro in the presence of β-hydroxybutyrate, one of the ketone bodies produced by diabetics. At 10 mM, β-hydroxybutyrate produced minor abnormalities and at 20 mM it produced major abnormalities in rat embryos.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02002633
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