Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Electronic Resource  (2)
  • oral contraceptives  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Recency, duration, and progestin content of oral contraceptives in relation to the incidence of endometrial cancer (Washington, USA) (1994)
    Springer
    Cancer causes & control 5 (1994), S. 227-233 
    Details
    ISSN: 1573-7225
    Keywords: Endometrial cancer ; oral contraceptives ; United States
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Women who have used combined oral contraceptives (COC) have a reduced risk of endometrial cancer relative to that of women who have never used oral contraceptives, but it is unclear whether the size of the reduction is influenced by the progestin content of the preparation. We analyzed data from two population-based case-control studies of endometrial cancer to investigate this question. Among women aged 40 to 59 years who were residents of King or Pierce Counties, Washington (United States), incident cases who were diagnosed during 1975–77 or 1985–87 were identified. Personal interviews were conducted with 316 such women and their responses compared with those of 501 controls who were selected by household surveys or random-digit dialing. A reduced risk of endometrial cancer associated with COC use was present only among users of five or more years' duration, and even then only in women who were not long-term users of unopposed postmenopausal estrogens. Among these women, the relative risk (RR) of endometrial cancer did not differ according to the progestin potency of the COC used: it was equally low for women who had used a COC with low progestin content (RR=0.2, 95 percent confidence interval [CI]=0.1–0.8) as for women who had used a COC with high progestin content (RR=0.3, CI=0.1–0.9). Our results argue that, if the reduced risk of endometrial cancer in long-term users of COCs is due to the progestins contained in these preparations, that amount of progestin in most COCs exceeds the threshold amount needed to produce this beneficial effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01830241
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Exogenous hormones, reproductive history, and colon cancer (Seattle, Washington, USA) (1994)
    Springer
    Cancer causes & control 5 (1994), S. 359-366 
    Details
    ISSN: 1573-7225
    Keywords: Case-control studies ; colorectal neoplasms ; estrogen replacement therapy ; menopause ; oral contraceptives ; parity ; USA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The associations between exogenous hormones, reproductive history, and colon cancer were investigated in a case-control study among women aged 30–62 years. The study was conducted in the Seattle, Washington (USA) metropolitan area between 1985 and 1989 and included 193 incident cases of colon cancer and 194 controls. There was little overall association between colon cancer and oral contraceptive use, parity, age at first birth, hysterectomy or oophorectomy status, or age at menopause. Use of noncontraceptive hormones at or after age 40, most likely hormone replacement therapy (HRT), was associated with decreased risk of colon cancer (adjusted odds ratio [OR]=0.60, 95 percent confidence interval [CI]=0.35–1.01), particularly among women with more than five years of use (OR=0.47, 95 percent CI=0.24–0.91). While results from previous studies have not been consistent, any protective effect of HRT against colon cancer would be important given the continuing debate over its potential risks and benefits.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01804987
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...