ISSN:
1434-193X
Keywords:
Asymmetric synthesis
;
Tetrahydroisoquinolines
;
Cyclizations
;
Diastereoselective alkylation of Amides
;
Phenylglycinol
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
-Bischler-Napieralski cyclisation of optically active β-substituted phenylethylamines 4a-c followed by diastereoselective reduction led to 1,4-disubstituted tetrahydroisoquinolines 6a-c and 8a-c. The same methodology afforded the 4-benzyl pyrroloisoquinolines 10.
Type of Medium:
Electronic Resource
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