ISSN:
1546-1696
Quelle:
Nature Archives 1869 - 2009
Thema:
Biologie
,
Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
Notizen:
[Auszug] Combinatorial libraries of rearranged hypervariable VH and VL sequences from nonimmunized human donors contain antigen specificities, including anti-self reactivities, created by random pairing of VHs and VLs. Somatic hypermutation of immunoglobulin genes, however, is critical in the generation of ...
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1038/nbt1067
Permalink