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  • Electronic Resource  (18)
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  • Electronic Resource  (18)
  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Endometrial thickness and reflectivity were assessed by transvaginal ultrasound in both spontaneous and hyperstimulated menstrual cycles. Two groups of women with ovulatory cycles were examined; women in group 1 had unexplained infertility and women in group 2 were having artificial insemination by donor because of reduced spermatogenesis; a third group (group 3) comprised women with tubal infertility undergoing hyperstimulation for in-vitro fertilization. There was no difference in endometrial thickness or reflectivity between the three groups. A basic pattern of endometrial appearance common to all cycles was found, consisting of hypoechoic, isocchoic and hyperechoic images, occurring in the early follicular, late follicular and luteal phases, respectively. In all three groups a positive correlation was found between proliferative phase plasma oestradiol concentration and endometrial thickness. Group 1 r= 0·403, P〈0·01; group 2 r= 0·439, P〈0·01; and group 3 r= 0·617, P〈0·01. There was a progressive increase in endometrial growth throughout the normal cycle until a plateau was reached 5 days after the LH surge. This pattern was also seen without acceleration of the process in hyperstimulated cycles, despite supranormal levels of oestrogen. Assessment of endometrial thickness is not a useful variable in monitoring hyperstimulated cycles. No aberrations of endometrial growth or pattern were observed in the women with unexplained infertility.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 91 (1984), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: An in-vitro penetration assay, which incorporates measurements of sperm motility and forward velocity, was used to investigate sperm-cervical mucus interaction in 20 couples with unexplained infertility. Evidence of impaired cervical mucus penetration was found in this group of patients and in seven couples the results correlated with previous assessment by laparoscopic sperm recovery. The impairment of cervical mucus penetration was found to be due to defective sperm function rather than to the quality of the cervical mucus itself. Of the criteria of semen quality measured in this study, sperm motility and the zona-free hamster egg penetration test showed significant correlations with cervical mucus penetration.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 96 (1989), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 87 (1980), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Sperm recovery from the peritoneal fluid was attempted in a group of infertile women in whom it was anticipated that all routine investigations would be normal (commonly referred to as ‘normal infertiles’). Forty-four couples were recruited into the study but in retrospect only 24 met the study criteria of normal semen, normal pelvis and appropriate timing. In 15 of these 24 patients, spermatozoa were covered from the peritoneal fluid, and so far seven have become pregnant. In the nine patients where spermatozoa were not recovered, none have so far become pregnant. There was no correlation between sperm recovery and the quality of the post-insemination cervical mucus examination. This test allows more accurate assessment of the ability of spermatozoa to reach the site of fertilization.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A total of 530 patients was reviewed six months after laparoscopic sterilisation by diathermy (235 patients) or silastic bands (295 patients). In the immediate post-operative period severe lower abdominal pain was more common in the patients who had silastic bands. There was one failure with diathermy and two with silastic bands. There were no differences in the nature or incidence of menstrual problems when the two methods were compared. In all, 40 per cent of patients reported an increase in menstrual blood loss and 26 per cent of patients an increase in menstrual pain, and this could not be attributed entirely to stopping oral contraception; 42 per cent of patients reported improvement in their sex lives after sterilisation, while 6.6 per cent reported deterioration mainly due to lack of libido. There was some regret about the operation in 5.1 per cent of patients.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 98 (1991), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective— To investigate menstrual symptoms in relation to pelvic pathology.Design— A prospective questionnaire-based study.Setting— Aberdeen Royal Infirmary, Scotland.Subjects— 1250 questionnaires were sent out prior to planned admission and 1200 women (96%) brought the completed questionnaires. They comprised 598 women undergoing laparoscopic sterilization, 312 having laparoscopy because of infertility, 156 having laparoscopy because of chronic pelvic pain and 134 women undergoing abdominal hysterectomy for dysfunctional uterine bleeding.Main outcome measures— The occurrence of dysmenorrhoea, menorrhagia, menstrual regularity, premenstrual spotting, deep dyspareunia and pelvic pain in women with either endometriosis and post infective pelvic adhesions or a normal pelvis.Results— Menorrhagia, menstrual irregularity and premenstrual spotting occurred with equal frequency in all groups. Deep dyspareunia, pain after intercourse and recurrent pain unrelated to menstruation or coitus was more common in women with endometriosis and those with post infective pelvic adhesions than in those with a normal pelvis. Dysmenorrhoea appears to be more prevalent among women having endometriosis.Conclusions— Menstrual symptoms, while raising a high index of suspicion for endometriosis, are not entirely reliable as indicators of disease. Dysmenorrhoea is the most common reported symptom in endometriosis sufferers. Diagnostic laparoscopy should be considered before institution of treatment in women complaining of pelvic pain and menstrual symptoms.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 98 (1991), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. Ninety-one women were asked to complete a standardized multiple choice questionnaire (modified from the Edinburgh Postnatal Depression Scale) to screen for anxiety and depression before and after legal abortion in early pregnancy achieved either by using mifepristone in combination with a prostaglandin (n= 54) or by vacuum aspiration under general anaesthesia (n= 37). Before abortion over 60% in both groups had high scores (compatible with psychiatric morbidity), but after the abortion there was a significant and equal fall in scores so that by 1 month 〈10% of either group had high scores. There was no difference between the two groups. Both methods of abortion were acceptable to the majority of women, although only 75% of the medical group indicated they would have the same method if a future termination was ever required, compared with 94% in the surgical group. However, in 13 women who had experience of both methods, the medical approach was preferred by 10 (77%). Thus, medical abortion is acceptable to the majority of women and is associated with the same low rate of short term psychiatric morbidity as has been recorded with surgical methods of termination, despite greater patient involvement and awareness of the abortion process.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 99 (1992), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To compare conservative versus prostaglandin management of prelabour rupture of the membranes (PROM) in healthy primigravid women at term.Design A prospective randomized study.Setting Labour Ward, Aberdeen Maternity Hospital.Subjects 230 primigravidae at term with PROM, 115 allocated to be treated conservatively and 115 to be managed with prostaglandin treatment.Interventions In the conservatively managed group the women were observed for up to 24 h after hospital admission with PROM. The actively managed group had PGE2 gel (2 mg) instilled into the posterior fornix and if contractions had not commenced, a further dose of PGE2 gel (1 mg) was instilled 6 h later. In both groups, if labour had not established 24 h after admission, intravenous oxytocin was given in escalating doses.Main outcome measures PROM to delivery interval, oxytocin augmentation, mode of delivery, maternal and neonatal infective morbidity.Results There was a significant reduction in the PROM to delivery interval in the women managed actively with PGE2 gel and fewer women in the PGE2 group required oxytocin augmentation (31%vs 51%). The two managements groups were comparable for intrapartum analgesia, antibiotic treatment, babies requiring admission to the special care nursery unit and delivery by caesarean section.Conclusion The early use of prostaglandin is associated with a significant reduction in PROM to delivery interval without a significant increase in infective morbidity or caesarean section rate. However, the advantages of the conservative approach should not be overlooked. More work is still needed in the management of those women where uterine activity fails to establish within 24 h after PROM.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 88 (1981), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A rapid luteinizing hormone (LH) radioimmunoassay (total time 4 h) has been developed and used to measure the preovulatory LH surge in 22 patients. Ovulation, assessed by laparoscopy or mini laparotomy, did not occur until at least 32 h after the start of the LH surge. This rapid LH radioimmunoassay provides a simple method of predicting ovulation for the correct timing of oocyte collection or artificial insemination.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 89 (1982), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. The results of a cervical mucus scoring system and of basal body temperature (BBT) chart interpretation were compared with those of a short-incubation radioimmunoassay for luteinizing hormone (LH) in 198 ovulatory menstrual cycles. The timing of the maximal cervical mucus score was similar to that of the LH peak in all but 7% of assessable cycles. In contrast, the timing of the nadir of the BBT differed widely from that of the LH peak in 45% of cycles with interpretable charts. These findings suggest that cervical mucus scoring might be useful for identifying the time of ovulation where LH assays are unavailable or where speed and economy are at a premium.
    Type of Medium: Electronic Resource
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