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  • 1960-1964  (20)
  • 1830-1839
  • 1963  (20)
  • 1833
  • Life and Medical Sciences  (20)
  • 1
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0362-2525
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Additional Material: 18 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: A histochemical and electron microscopic study of the liver in rats fed a diet containing excess amounts of copper was made to demonstrate the intrahepatic, intralobular and intracellular distribution of the metal.Histochemically copper was demonstrated first at the periphery of the hepatic lobuleand appeared throughout the lobule as the amount of metal increased. Within the hepaticcell copper was demonstrated in the pericanalicular cytoplasm. As the amount of metal in the liver increased occasional perinuclear caps or plaques were formed. Hematoxylin and eosin stained sections of livers with high copper content differed from normal by the presence of light brown pigment. Copper was demonstrated histochemically in the spleen and kidneys of copper fed animals as well as in the liver.Electron microscopic studies of the hepatic cells from copper fed rats revealed numerous irregular dense bodies and pigment granules in the pericanalicular cytoplasm. The dense bodies were enclosed by a single membrane and contained granular material. The appearance of these pericanalicular bodies was associated with loss of histochemical acidphosphatase activity.
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 147 (1963), S. 5-13 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Four kinds of abnormal pulmonary and three kinds of abnormal semilunar valves are described from pig and human embryos of an age equivalent to the first human trimester. The pulmonary valves include bicuspid forms resulting from the absence of an anterior cusp, from the fusion of left and anterior cusps and from the fusion of left and right cusps; also dome-shaped valves. The aortic valves include bicuspid forms resulting from the absence of the non-coronary cusp and from the fusion of right and left cusps. All are discussed in the light of accompanying heart anomalies and a re-examination of normal cusp development. Embryonic abnormal pulmonary valves are generally linked with early stages of Fallot's tetralogy. They are caused by an arrest in heart development and the changed hemodynamic conditions that result from it. Embryonic abnormal aortic valves are caused by an arrest in heart development and an abnormal degree of coarctation of the aorta. The evidence from embryos supports the general belief that abnormal pulmonary cusps of all ages, when not caused by infection, are of congenital origin. Some aortic abnormal valves are also of congenital origin, but are hard to distinguish from similar ones produced after birth by postnatal coarctation.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 149-155 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Enlargement of the ulnar nerve behind the medial epicondyle was noticed in museum and demonstration specimens and also in the dissection room cadavers. An investigation was carried out to study the incidence and character of the enlargement entirely from fresh autopsy cases, which included 400 ulnar nerves from 200 autopsy cadavers of Chinese subjects of all ages. The enlargement was graded into three categories  -  slight, moderate, and marked. Histological sections, 40 μthick and stained with H. & E., were examined. Twenty nerves from ten adult bodies were tested under stress for extensibility along the length of the nerve. Fortynine per cent of the ulnar nerves and 60.5% of cadavers of the total sample showed this enlargement, the incidence being greater in males than in females and slightly greater in the right limb than the left limb. Slight and moderate enlargement occurred in all ages; marked enlargement occurred only in ages over 35. The enlargement presented a normal histological picture; the enlargement was due to an increase of connective tissue present. The experimental results of extensibility along the length of the nerve showed the retro-epicondylar region, whether enlarged or not, to be more extensible than the rest of the nerve. While there seemed to be a tendency of a decrease of extensibility with enlargement, the correlation between extensibility and enlargement was insignificant statistically.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Breeding records of the ia strain of rats have shown interesting cases of anomalous pregnancies where second litters are delivered either before or soon after weaning the first litter. This strain is characterized by a retardation of bone resorption which is inherited as a simple Mendelian recessive factor.Heterozygous and homozygous males are mated with females of both genotypes. One male and four females are kept in a breeding cage and the female rat is isolated either in the late stage of pregnancy or soon after birth of the litter.Nineteen anomalous pregnancies have been reported and the occurrence of the anomaly has been attributed to copulation during pregnancy. The ancestry of 13 cases is traced to four animals, two homozygous males and two heterozygous females, and the genetic pattern has been demonstrated.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Dividing cells have been labeled in three week old chicks with H3-thymidine and observed through radioautography at different time intervals and also under varied nutritional and hormonal conditions.After two hours mostly primitive cells were labeled (Mesenchymal cells, fibroblasts, chondroblasts, hemopoietic precursors).Labeled osteoclasts and osteoblasts were abundant after one and two days and their number decreased thereafter.Labeled osteocytes were present at two and four days but rarely thereafter. Osteocyte maturation was delayed in rickets.The osteoclasts showed a larger proportion of labeled nuclei in the Vitamin D treated birds as compared to the rachitic group. Otherwise the rate of appearance and disappearance of labeled nuclei in osteoclasts was constant in the three groups of chicks.Osteoclasts during their life span, renew their nuclei by annexation of young ones as older nuclei degenerate.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In the forelimbs, the sequence of blastemal condensation is: scapula and humerus, ulna, digit IV, digit V, radius, digit III, digit II, digit I. In the hind limb, the sequence is: innominate bone and femur, fibula, digit IV, digit V, tibia, digit III, digit II, digit I. The sequence described may lead to loss of preaxial parts of the limb in cases of severe over-all reduction of limb bud material due to genetic or teratogenic agents. The main reason why ectrodactyly and polydactyly in the mouse are usually preaxial is the localization for some unknown reason of alterations in growth rate in the preaxial margin of the footplate. However, the fact that blastemal condensations begin postaxially will tend to confine these and similar skeletal anomalies of the limb to the preaxial part.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 145 (1963), S. 1-5 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Two direct branches of the brachiocephalic artery are frequently present in the dog. These are described in 33 dogs and their incidence recorded. One supplies the lower cervical trachea and esophagus and the other the thymus gland and sometimes the pericardium. Suggested names are “Tracheoesophageal” and “Thymopericardial” branches of the brachiocephalic. The embryology of the blood vessels of the esophagus is discussed and the identification of the tracheoesophageal with a secondary anastomotic vessel is considered most likely. Occasional branches from the brachiocephalic artery in man are reviewed. The Arteria Thyroidea Ima seems to bear the closest relationship to this vessel described in the dog. The value of this study in relation to heart-lung preparations and to experimental surgery of the esophagus is suggested.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 113 (1963), S. 417-445 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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