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  • 2000-2004  (26)
  • 1990-1994
  • 1905-1909  (3)
  • 2003  (12)
  • 2002  (14)
  • 1907  (3)
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Material
Years
  • 2000-2004  (26)
  • 1990-1994
  • 1905-1909  (3)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Detection of High-Risk Atherosclerotic Coronary Plaques by Intravascular Spectroscopy (2003)
    350 Main Street , Malden , MA 02148 , USA . : Blackwell Science Inc
    Journal of interventional cardiology 16 (2003), S. 0 
    Details
    ISSN: 1540-8183
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Multiple technologies are under development to identify plaque composition and vulnerability. This review article is intended to provide basic knowledge to the interventional cardiologist and the clinician about spectroscopy. The concept of light, the wavelength unit and the electromagnetic spectrum are discussed. Different types of spectra analysis including nuclear magnetic resonance, Raman, fluorescence and diffuse reflectance near-infrared spectroscopy are then carefully reviewed. Experimental data to identify atherosclerotic plaque composition for each of these techniques is provided. Potential benefits and challenges are addressed. Finally, diffuse reflectance near-infrared spectroscopy is discussed in more detail as a promising technique to characterize plaque vulnerability in humans. (J Interven Cardiol 2003;16:243–252)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0854.2003.8040.x
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Marking patch tests sites: description of a practical, clean, durable and inexpensive method (2003)
    Oxford, UK; Malden , USA : Munksgaard International Publishers
    Contact dermatitis 49 (2003), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We propose an original method to mark patch test sites. A transparency is applied on the patient's back, surrounding patch tests, immediately after their application. Marks are performed with an erasable pen on test sites and on permanent skin lesions like naevi. For further readings performed after patch test removal, the transparency applied on the patient's back permits the attribution of a positive reaction. This method is clean (without ink marks on skin and without contamination of clothing), more comfortable for the patient (allowing back washing immediately after the 1st reading, never inducing allergy to inks), durable (permitting delayed readings after several days or weeks) and inexpensive (because transparencies can be reused).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.0105-1873.2003.0261.x
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Topological Spatio–Temporal Reasoning and Representation (2002)
    Boston, USA and Oxford, UK : Blackwell Publishers Inc
    Computational intelligence 18 (2002), S. 0 
    Details
    ISSN: 1467-8640
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Computer Science
    Notes: We present here a theory of motion from a topological point of view, in a symbolic perspective. Taking space–time histories of objects as primitive entities, we introduce temporal and topological relations on the thus defined space–time to characterize classes of spatial changes. The theory thus accounts for qualitative spatial information, dealing with underspecified, symbolic information when accurate data are not available or unnecessary. We show that these structures give a basis for commonsense spatio–temporal reasoning by presenting a number of significant deductions in the theory. This can serve as a formal basis for languages describing motion events in a qualitative way.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1467-8640.00196
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Co-determination and strategic integration in German firms (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Human resource management journal 12 (2002), S. 0 
    Details
    ISSN: 1748-8583
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Looking at the economic development and importance of German companies in Europe, one might expect that an important aspect of a good economic performance is a well-functioning HR system. Although a number of scholars claim this, the empirical evidence seems to point to the opposite. Several comparative studies have found that HRM in German companies is less strategically integrated and proactive than that of comparable firms in other countries. This article argues that the empirical results reported fail to grasp the essence of HRM in German firms. This lacuna is partly due to the co-determination structure. HRM in large German firms has to be evaluated within the co-determination structure, with the Betriebsrat (works council) being an important actor. For German firms co-determination might even be a strategic resource. By examining this issue within such a framework, a more favourable picture of HR integration in German firms emerges.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-8583.2002.tb00072.x
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    COCHLEAR IMPLANTS: Some Likely Next Steps* (2003)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biomedical Engineering 5 (2003), S. 207-249 
    Details
    ISSN: 1523-9829
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Technology , Medicine
    Notes: Abstract The history of cochlear implants is marked by large improvements in performance, especially over the past two decades and especially due to the development of ever-better processing strategies. Although the progress to date has been substantial, present devices still do not restore normal speech reception, even for top performers and particularly for listening to speech in competition with noise or other talkers. In addition, a wide range of outcomes persists, with some patients receiving little benefit using the same devices that support high levels of speech reception for others. The purpose of this review is to describe some likely possibilities for further improvement, including (a) combined electric and acoustic stimulation of the auditory system for patients with significant residual hearing, (b) use of bilateral implants, (c) a closer replication with implants of the processing steps in the normal cochlea, and (d) applications of knowledge about factors that are correlated with outcomes to help patients presently at the low end of the performance scale.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.bioeng.5.040202.121645
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    MOLECULAR PATHOGENESIS OF LUNG CANCER (2002)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Physiology 64 (2002), S. 681-708 
    Details
    ISSN: 0066-4278
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Biology
    Notes: Abstract Lung cancer is the most common cause of cancer death in the United States, killing more than 156,000 people every year. In the past two decades, significant progress has been made in understanding the molecular and cellular pathogenesis of lung cancer. Abnormalities of proto-oncogenes, genetic and epigenetic changes of tumor suppressor genes, the role of angiogenesis in the multistage development of lung cancer, as well as detection of molecular abnormalities in preinvasive respiratory lesions, have recently come into focus. Efforts are ongoing to translate these findings into new clinical strategies for risk assessment, chemoprevention, early diagnosis, treatment selection, and prognosis and to provide new targets and methods of treatment for lung cancer patients. All these strategies should aid in reducing the number of newly diagnosed lung cancer cases and in increasing the survival and quality of life of patients with lung cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.physiol.64.081501.155828
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    COCHLEAR IMPLANTS: Some Likely Next Steps* (2003)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Biomedical Engineering 5 (2003), S. 207-249 
    Details
    ISSN: 1523-9829
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Technology , Medicine
    Notes: The history of cochlear implants is marked by large improvements in performance, especially over the past two decades and especially due to the development of ever-better processing strategies. Although the progress to date has been substantial, present devices still do not restore normal speech reception, even for top performers and particularly for listening to speech in competition with noise or other talkers. In addition, a wide range of outcomes persists, with some patients receiving little benefit using the same devices that support high levels of speech reception for others. The purpose of this review is to describe some likely possibilities for further improvement, including (a) combined electric and acoustic stimulation of the auditory system for patients with significant residual hearing, (b) use of bilateral implants, (c) a closer replication with implants of the processing steps in the normal cochlea, and (d) applications of knowledge about factors that are correlated with outcomes to help patients presently at the low end of the performance scale.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.bioeng.5.040202.121645
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Root elongation and branching is related to local hexose concentration in Arabidopsis thaliana seedlings (2002)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 25 (2002), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Root architecture can be profoundly affected by the carbon availability in the plant. We hypothesized that this effect could be mediated by the carbon status of root cells involved in elongation and branching processes. Arabidopsis thaliana plants were grown at several photosynthetic photon flux densities (PPFD) and were supplied with various sucrose concentrations in the root medium. Hexose and sucrose concentration was estimated in individual roots in the apical growing region of the primary root and of secondary roots as well as in the zone of primordia development. Local sugar concentration was high in fast-growing and in highly branched roots and robust relationships between root elongation rate or branching and hexose concentration (but not sucrose) were found that were common to all situations experienced. Moreover, these relationships accounted for the plant-to-plant variability within a treatment as well as for the variability among individual secondary roots within a plant. These results support the view that local hexose concentration integrates changes in carbon availability from several sources and acts as a signal to induce at least part of the response of the root architecture to the environment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2002.00912.x
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Temporal responses of Arabidopsis root architecture to phosphate starvation: evidence for the involvement of auxin signalling (2003)
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 26 (2003), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The ability of the root system architecture to respond to nutrient availability is a key adaptative behaviour allowing plants to cope with environmental conditions. On the basis of single time point comparisons, the response to phosphate deprivation was previously shown to involve both the primary and lateral roots of Arabidopsis. In this work, the temporal pattern of Arabidopsis root responses to phosphate starvation was investigated. Daily scanning of roots showed that changes in architecture were largely due to the alterations of time-based growth parameters, namely a decrease in the elongation rate of the primary root opposed to an increase in the elongation rate of lateral roots and a decrease in the number of initiated lateral roots. In addition, another identified response was a decrease in the proportion of lateral roots showing early growth arrest. All these changes occurred within a short period of approximately 3 d. In addition, the root morphology comparison with the auxin-resistant mutant axr4, the auxin-treatment of phosphate-starved plants and a limited transcriptome analysis supported the conclusion that auxin signalling was involved in the adaptive response of the root system architecture to phosphate deprivation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2003.01030.x
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Transcription factor genes with expression correlated to nitrate-related root plasticity of Arabidopsis thaliana (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Plant, cell & environment 26 (2003), S. 0 
    Details
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The root response to changes in nitrogen availability was examined in Arabidopsis thaliana. Plants grown on vertically oriented Petri plates with nutrient media containing either 10 or 0.5 mm KNO3 supplemented with 5 mm glutamine were analysed for changes in root architecture, morphology and nitrogen status compared to plants grown on 0.5 mm KNO3. Fourteen-day-old 10 mm KNO3-grown plants displayed a decrease in number, length and density of lateral roots, had the highest tissue NO3– content, but no change in amino acid composition. Lateral root development was arrested at a stage after the initiation of primordia but prior to emergence. In contrast, plants grown on 0.5 mm KNO3 supplemented with glutamine had a slightly higher number and density of lateral root primordia and lateral roots, lower root NO3– content, and higher tissue glutamine content. A macro-array containing 126 putative A. thaliana transcriptional factor expressed sequence tags was used to screen for regulatory genes with expression correlated to the root plasticity response. Genes for a basic leucine zipper (bZIP) and a LIM transcription factor were identified and via Northern analysis it was confirmed that their expression is preferentially observed in the roots and correlated to the root response to nitrate availability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-3040.2003.00977.x
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    Paper (German National Licenses)
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