Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2005-2009
  • 2000-2004
  • 1975-1979  (2)
  • 1950-1954  (3)
  • 1930-1934
  • 1976  (2)
  • 1950  (3)
Source
Material
Years
  • 2005-2009
  • 2000-2004
  • 1975-1979  (2)
  • 1950-1954  (3)
  • 1930-1934
Year
  • 1
    Electronic Resource
    Electronic Resource
    SODIUM AND CHLORIDE FLUXES IN SYNAPTOSOMES IN VITRO (1976)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 26 (1976), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Synaptosomes incubated in a physiological saline extrude sodium and take up potassium. As would be expected this process is completely blocked by metabolic inhibitors such as cyanide and iodoacetate. However, when metabolic inhibitors are replaced by ouabain (100 μM) there is an increase in the steady state intrasynaptosomal sodium and chloride content even though there is no change in the potassium content. The increases are prevented when synaptosomes are incubated with metabolic inhibitors in addition to ouabain. There is therefore a ouabain-insensitive process that transports sodium, chloride and concomitantly water into synaptosomes. It appears not to function when the supply of metabolic energy is inhibited. The diuretic furosemide (1 mM) in the presence of ouabain inhibits the entry of sodium and chloride without affecting the intrasynaptosomal potassium concentration. Ethacrynic acid (1 mM) has a somewhat similar effect but in addition appears to damage the synaptosome membrane.Kinetic measurements were made of the uptake of sodium, potassium and chloride under conditions of metabolic inhibition and the permeability constants of the membrane determined. Values of 0.068, 0.117 and 0.032 × 10-6 (cm s-1) were found for the permeability constants of the membrane to (respectively) sodium, potassium and chloride. Measurements of the rate of uptake in the presence of ouabain revealed an inwardly directed sodium and chloride flux of 5-20 pmol cm-2 s-1. Calculation of the fluxes from the steady state ion concentrations also reveals an inwardly directed sodium and chloride flux, though of lesser magnitude. The influx of water is less than would be expected to preserve osmotic equality suggesting that the translocation of sodium and chloride is the primary event. Although its function remains uncertain the flux has a considerable effect on the ion content of synaptosomes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1976.tb06480.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The Claims of Reason (1950)
    Cambridge : Cambridge University Press
    Philosophy 25 (1950), S. 114-133 
    Details
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Notes: I have chosen my topic for this evening with an eye to something rather more than its intrinsic philosophical interest. Modern man, as we are all painfully aware, is facing a crisis of peculiar gravity. Perhaps the odds are not so very heavy against a third world war followed by world collapse into anarchy and barbarism. At such a time the philosopher is bound to ask himself whether there is no contribution which his science can make towards the succour of civilization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0031819100008020
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Mr. Edwards on “ordinary language and absolute certainty” (1950)
    Springer
    Philosophical studies 1 (1950), S. 60-63 
    Details
    ISSN: 1573-0883
    Source: Springer Online Journal Archives 1860-2000
    Topics: Philosophy
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02216992
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    facet.materialart.
    Unknown
    Mr. Edwards on "Ordinary Language and Absolute Certainty" (1950)
    Minneapolis : Periodicals Archive Online (PAO)
    Philosophical Studies. 1 (1950) 60 
    Details
    ISSN: 0031-8116
    Topics: Philosophy
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:6193-1950-001-00-000011
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    facet.materialart.
    Unknown
    THE STUDY OF LAW IN SOCIETY IN BRITAIN (1976)
    Beverly Hills, Calif. : Periodicals Archive Online (PAO)
    Law and society review. 10:4 (1976:Summer) 547 
    Details
    ISSN: 0023-9216
    Topics: Law
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:d430-1976-010-04-000005
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...