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  • 1965-1969  (2)
  • 1968  (2)
Material
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  • 1965-1969  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 1249-1253 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Regression of osteitis fibrosa has been observed in a uremic patient after hemodialysis for six months. The exchangeable calcium was found to be 3.15 meq/kg and bone accretion rate 0.61 meq/kg/day in a control group of uremic patients without osteitis fibrosa under chronic hemodialysis. In contrast both values were markedly higher in the above patient with osteitis fibrosa and a control patient with osteitis (exchangeable calcium 10.3 meq/kg and 8.34 meq/kg; accretion rate 6.18 and 6.92 meq/kg/day). After hemodialysis for six months the exchangeable calcium of the patient decreased by 49.5% and his accretion rate by 35%. His intestinal absorption was high (60%) in contrast to uremic controls (35.5%). When measuring the regional distribution of47Ca in a body-counter the maximum of activity was found in the head-region in cases with osteitis fibrosa. This was shown to be due to rapid uptake of activity by the bones of the skull. Parathyroid hormone levels and serum hydroxyprolin were markedly increased, ultrafiltrable calcium was unchanged.
    Notes: Zusammenfassung Bei einem urämischen Patienten wurde die Rückbildung einer Ostitis fibrosa unter chronischer Hämodialyse beobachtet. Austauschbares Calcium (10,3 mÄq/kg bzw. 8,34 mÄq/kg) und Knocheneinbaurate (6,8 mÄq/kg/die bzw. 6,92 mÄq/kg/die) waren bei dem Patienten (und einem Kontrollpatienten mit renaler Ostitis fibrosa) deutlich erhöht. Nach Dialysebehandlung und Gabe von Aludrox verringerte sich das austauschbare Calcium um 49,5% und die Einbaurate um 35%. In einer Kontrollgruppe von Patienten mit terminaler Niereninsuffizienz unter Dauerdialyse wurde demgegenüber ein austauschbares Calcium 3,15 mÄq/kg und eine Knocheneinbaurate von 0,61 mÄq/kg gefunden. Das Maximum der im Ganzkörperprofil gefundenen Aktivitätsverteilung von47Ca — gemessen im Ganzkörperzähler — war bei den Patienten mit renaler Ostitis fibrosa kopfwärts verschoben; mit87mSr ließ sich die Anreicherung der Aktivität in den Schädelknochen nachweisen. Die Calcium-Absorption war bei dem Patienten (60%) deutlich höher als bei der urämischen Kontrollgruppe (35,5%). Die Serumparathormonspiegel und Serumhydroxyprolinspiegel waren bei renaler Ostitis fibrosa deutlich erhöht, das ultrafiltrable Calcium unverändert.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 24 (1968), S. 433-434 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The influence of biguanides on glucoseoxidation was studied in intima-preparations of rabbit aortae. With high doses (500 µg/ml) an inhibition of CO2-formation predominantly from position C-1 of glucose was found. With 4 µg/ml there was no significant change of CO2-for-mation from glucose.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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