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  • 1985-1989
  • 1970-1974  (5)
  • 1970  (5)
Material
Years
  • 1985-1989
  • 1970-1974  (5)
Year
  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 226 (1970), S. 626-628 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] An appropriate physical model- incorporating transit time delays has been analysed, and yields the continuity equations which follow (ref. 7 and my unpublished work). n = nen(Gv)ne ? nen(av)ne (1) ne= ? n ne(Gv)ne + nne(Gv)ne (2) where ne and n are, respectively, the time averaged electron and ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 26 (1970), S. 395-396 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé On décrit deux rares variations structurelles: cristalloïdes cytoplasmiques intracellulaires et mitochondries géantes, observées dans les cellules marginals de la muqueuse gastrique du furet. Les cristalloïdes cytoplasmiques sont probablement en rapport avec la dégénération mitochondrielle, et les mitochondries géantes sont un caractère aberrant.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 15 (1970), S. 1055-1065 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The mechanisms involved in the pathogenesis of a new model for experimental gastric ulcer after epinephrine administration to the rat were evaluated. That the lesions depended upon acid was demonstrated by their prevention or reduction after bilateral vagotomy, or the administration of an anticholinergic or antacid, and by the reappearance of lesions when artificial gastric acid was infused in the absence of vagal innervation. The probable role of an epinephrine-induced vascular change related to excitation of α-receptor sites was suggested by the protection afforded by the administration of α- but not β-adrenergic blocking agents. The complex involvement of histamine in the pathogenesis was suggested by the protection afforded by both a histidine decarboxylase blocking agent, brocresine, and by aminoguanidine, which inhibits the catabolism of histamine. Adrenalectomy and hypophysectomy both afforded significant protection against ulceration, an effect which may have been mediated through the observed inhibition of gastric acid secretion.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 15 (1970), S. 1073-1081 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases of fundal gastric carcinoma producing a typical picture of achalasia, including a positive Mecholyl test, are described. The differential diagnosis of both conditions is discussed. Hypersensitivity to cholinergic agents should be interpreted only as representing anatomic and/or physiologic derangement of the myenteric plexus of the esophagus and should not be considered as pathognomonic of achalasia. Fundal carcinoma producing infiltrating lesions at the level of the myenteric plexus of the esophagus may closely simulate primary achalasia. The evaluation of achalasia in a given patient is not complete without careful radiologic and endoscopic studies with biopsy and cytologic sampling of any suspicious area.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 15 (1970), S. 261-270 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The influence of the vasoactive catecholamines, epinephrine and norepinephrine, has been investigated in regard to the comparative ulcerogenicity on the gastric glandular mucosa of the rat. The unique extensive, hemorrhagic necrosis, and ulcerations which appear in the fundus—but not the antrum—following single injections of these drugs are readily quantified because of the continuous nature of the lesion. A standard assay has been developed with this new ulcer model, which results in extensive mucosal ulceration (43% of fundus with lesions) in 100% of treated animals after only 5 hr. The optimal procedure requires the single intraperitoneal epinephrine injection of 0.4 mg/kg to young adult Sprague-Dawley rats 4 hr after pylorus occlusion, and the sacrifice of animals 1 hr after injection. This experimental gastric lesion is dependent upon the presence of gastric acid, and is completely inhibited by bilateral vagotomy, and almost completely inhibited by the presence of a magnesium-aluminum hydroxide gel-type antacid.
    Type of Medium: Electronic Resource
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