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  • 1995-1999  (5)
  • 1970-1974  (6)
  • 1965-1969
  • 1997  (5)
  • 1972  (6)
  • 1
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 94 (1972), S. 4028-4030 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Personnel psychology 25 (1972), S. 0 
    ISSN: 1744-6570
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Psychology
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-041X
    Keywords: Key words Ascidian ; Serine protease ; Differential display ; Gene expression ; In situ hybridization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  We have studied gene expression during ascidian embryonic development using the technique of differential display and isolated partial cDNA sequences of 12 genes. Developmental regulation of these genes has been confirmed by northern hybridization analysis. Further cDNA cloning and sequence analysis of an mRNA that is present during gastrulation, neurulation and tailbud formation reveals that it encodes a novel serine protease containing a single kringle motif and catalytic domain. The spatial expression of this gene, designated Hmserp1, is restricted to precursor cells of the epidermis. The structure and expression of Hmserp1 is discussed in relation to possible functions during development.
    Type of Medium: Electronic Resource
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  • 5
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    Leiden : Periodicals Archive Online (PAO)
    Arabica. 19 (1972) 78 
    ISSN: 0570-5398
    Topics: Linguistics and Literary Studies , Ethnic Sciences , History , Theology and Religious Studies
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Wood science and technology 6 (1972), S. 1-42 
    ISSN: 1432-5225
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The study of adhesion in wood and wood-based products becomes increasingly important as work continues toward greater utilization of our total forest resources. The present quality of adhesively bonded wood products will be improved in order to achieve bond quality that harnesses the full strength of wood and, more importantly, leads to greatly enhanced bond durability. These goals will primarily be reached through developing a chemically-anchored bond interface and resin systems that are more flexible and compatible in the cured state. This paper presents a selected review of current findings and thought in the general field of surface and interfacial adhesion, and attempts to give a detailed look at efforts in wood science to understand basic phenomena of adhesion in wood and apply them in achieving a strong and durable bonded state. A brief introductory discussion on the nature of the basic forces involved in all interactions between materials at the atomic and molecular level is included. The general field of interfacial adhesion is reviewed in order to find important factors basic to the adhesion phenomena that have survived long, intensive research efforts in this field. Finally, an in-depth look is taken at interfacial adhesion in wood science.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2242
    Keywords: Key words Triticum aestivum ; Doubled haploids   ; Intervarietal map ; Distortion segregation ; Genetic map comparison
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  An intervarietal molecular marker map covering most of the nuclear genome was developed in Triticum aestivum. One hundred and six androgenetic-derived doubled haploid lines obtained from the F1 between monosomics of ‘Chinese Spring’ and ‘Courtot’ were analysed for genetic mapping. The map covered 18 of the 21 chromosomes with an identical distribution of markers in the A and B genome, and only small segments of the D genome. Distorted markers were mapped using Bailey’s 2-point method and revealed skewed regions on 1A, 1DS, 2A, 2B, 4AS and 6B. Comparison with a wide cross [‘Opata’×Synthetic hexaploid (T. tauschii/‘Altar 84’)] showed colinearity for markers on homologous chromosomes, but revealed a large proportion (25%) of markers mapped on non-homoeologous chromosomes, i. e. heterologous markers. The origin of the material and distortion segregation are discussed with particular emphasis on investigations of D-genome markers.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 14 (1997), S. 810-814 
    ISSN: 1573-904X
    Keywords: formoterol ; radiation treatment ; ESR spectroscopy ; dosimetry ; storage ; HPLC ; degradation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. Radiation sterilization is becoming increasingly popular for the sterilization of many pharmaceutical products. We have investigated the gamma radiation induced effects on formoterol fumarate by HPLC and ESR spectroscopy. Results and Discussion. Numerical simulation of the evolution of the ESR signal versus dose was performed using linear regression, quadratic fit and power function. The shape of the dosimetric curve is linear in the range 5−30 kGy. Owing to the weak number of free radicals generated during the irradiation, the accuracy of measurements is low. For a dose of 25 kGy, discriminating irradiated from unirradiated samples is possible if the storage period is less than 250 days. The comparison between chromatographic profiles of irradiated and unirradiated samples showed minor differences. Conclusions. From our preliminary results, radiosterilization of formoterol fumarate may be technically feasible. Estimation of the irradiation dose by ESR may be possible but, due to the weak number of free radicals generated during the irradiation, the accuracy of measurements appeared low.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Pharmaceutical research 14 (1997), S. 1186-1191 
    ISSN: 1573-904X
    Keywords: radiosterilization ; ascorbic acid ; ESR ; dosimetry ; decay of radicals
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. As an alternative to heat and gas exposure sterilization, ionizing radiation is gaining interest as a sterilization process for medicinal products. The aim of this work was to develop equations to describe the ESR curves versus dose and storage time after gamma irradiation of ascorbic acid. Several ESR data sets previously acquired in this laboratory were adopted to check the performance of the models. Results. Limit of detection and limit of discrimination are respectively 0.5 kGy and 2 kGy for ascorbic acid. Linear regression is applicable for doses lower than 25 kGy. Since the radiation dose selected must always be based upon the bioburden of the products and the Degree of Sterility required (ANSI/AAMI/ISO 11137), doses in the range 5−25 kGy could be investigated and linear regression would appear to be the least expensive route to follow and gives good results. Quadratic fit, power function, exponential function and bi-exponential functions are of more general applicability to predict irradiation dose. Decay kinetics for radicals versus storage were considered. Nonhomogeneous kinetics with time-dependent rate (diffusion-controlled second-order reaction) and bi-exponential function appeared valid to reproduce the experimental data. Discrimination between irradiated and unirradiated ascorbic acid is possible after a storage of 800 days. Conclusions. It is worth noting that, at present, ESR is the only technique which proves to be suitable for identification and quantification purposes in irradiated pharmaceuticals. Moreover, other features such as sensitivity, precision, ease and non-destructive readout make ESR superior to other proposed analytical techniques.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Digestive diseases and sciences 17 (1972), S. 875-880 
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases of esophageal obstruction occurring with epidermolysis bullosa of the dystrophic type are presented. The mode of definitive therapy, retrograde dilation in one and colonic transplant in the other, was determined by considerations of pathology, age and nutritional state.
    Type of Medium: Electronic Resource
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