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  • 2000-2004
  • 1970-1974  (1)
  • 1972  (1)
  • Protein-Phosphokinase  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 50 (1972), S. 1114-1115 
    ISSN: 1432-1440
    Keywords: Platelets ; Cyclic AMP ; Protein-phosphokinases ; Blutplättchen (Mensch) ; c-AMP ; Protein-Phosphokinase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung In menschlichen Blutplättchen wurde eine Enzymreaktion gefunden, die die Eigenschaften typischer Proteinkinasen anderer Zellen und Gewebe zeigt: Phosphorylation basischer Proteine (Histon) in Serin- und Threoninresten, Magnesiumabhängigkeit und Stimulation durch Adenosin 3′,5′-monophosphat. Dieses Enzym könnte ein wichtiges Bindeglied zwischen der intracellulären c-AMP-Konzentration und der Plättchen-Funktion darstellen.
    Notes: Summary An enzyme reaction in human platelets is demonstrated which possesses the properties of protein-phosphokinases isolated from other cells: phosphorylation of basic proteins in phosphoserine and -threonine linkages, magnesium dependency and stimulation by adenosine 3′,5′-monophosphate. It is suggested that this enzyme might be responsible for the expression of the cAMP effects on the platelets.
    Type of Medium: Electronic Resource
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