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Attempted hybridizations with senescent human fibroblastsSupported by USPHS grants CA-04670 and AM-13655. (1973)

Littlefield, John W.

New York, NY [u.a.] : Wiley-Blackwell

Journal of Cellular Physiology 82 (1973), S. 129-131

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ISSN: 0021-9541

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: If the aging of diploid human fibroblasts reflects stable genetic or epigenetic changes which are few in number and different in different cells, then complementation could occur in hybrids between individual senescent cells. However neither pairs of aged fibroblasts nor even pairs of young and senescent fibroblasts produce viable hybrids under conditions known to promote cell fusion.

Additional Material: 1 Tab.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jcp.1040820115

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