ISSN:
1432-1424
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Chemie und Pharmazie
Notizen:
Summary Incubation of the salivary glands of the larvae ofDrosophila hydei in a control medium containing 2×10−3 m cyclic adenosine monophosphate (cAMP) induces a considerable increase in passive electrical cel communication. This is caused by a decrease in permeabilty of the nonjunctional membrane part, together with an increase of the permeability of the low-resistance junctions. Similar changes in intercellular communication in the salivary gland ofDrosophila hydei were seen in a majority of experiments in which 10−3 m dibutyryl cycli adenosine monophosphate (dBcAMP), 5×10−3 m theophylline or ecdysterone (100 μg/ml) were added to the control medium. Hyperpolarization of the gland cells can be observed concomitant with the increase in communication. A hypothesis is discussed for a possible molecular regulation of passive electrical cell communication in which the intracellular cAMP level plays a significant part.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01869981
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