ISSN:
1432-2307
Keywords:
Juxtaglomerular apparatus
;
Macula densa basal area
;
Juxtaglomerular contact areas
;
Addison's disease
;
Bartter's syndrome
;
Conn's syndrome
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Continuing and supplementing previous morphometric studies on the Juxtaglomerular apparatus (JGA) of normal kidneys we have now investigated semi-thin serial sections of each 10 hyperplastic and hypertrophied JGAs in Addison's disease and in Bartter's syndrome, as well as 8 atrophic JGAs in Conn's syndrome. With the exception of Bartter's syndrome, where in only two out of ten JGAs the efferent arteriole, and in none of them the afferent arteriole touches immediately the macula densa, there is an almost regular direct contact between the hilar arterioles and the macula densa like in normal kidneys. The Goormaghtigh cell field invariably touches the macula densa. In Bartter's syndrome, but not in Addison's disease, a considerable enlargement of the macula densa was measured, associated with an exceptional enlargement of the Goormaghtigh cell field. In all cases examined here about 40–60% of the basal area of the macula densa do not have any direct contact with other structures forming the JGA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00430807
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