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  • 2000-2004
  • 1975-1979  (5)
  • 1977  (5)
  • 1
    Electronic Resource
    Electronic Resource
    Bis(trifluoromethyl)sulfimide, bis(trifluoromethyl)-N-alkylsulfimides, and bis(trifluoromethyl)-N-alklysulfoxyimides (1977)
    s.l. : American Chemical Society
    Inorganic chemistry 16 (1977), S. 33-35 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic50167a008
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Nile Cone: Late Quaternary stratigraphy and sediment dispersal (1977)
    [s.l.] : Nature Publishing Group
    Nature 266 (1977), S. 129-135 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cyclic nature of Late Quaternary Nile Cone sediments is a response to major climatic oscillations, including marked changes in sea level, Nile River discharge and sediment influx and water mass stratification. Deposits have accumulated most rapidly north-west of the Nile Rosetta Branch since ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/266129a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Changes in morphine self-administration after brainstem lesions in rats (1977)
    Springer
    Psychopharmacology 52 (1977), S. 151-156 
    Details
    ISSN: 1432-2072
    Keywords: Morphine ; Self-administration ; Substantia nigra ; Midbrain raphe nuclei ; Locus coeruleus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Rats were trained to bar press for intravenous infusions of morphine sulfate during 1-h daily test sessions. Rates of morphine self-administration were reduced by bilateral lesions of the substantia nigra and enhanced by lesions of the medial raphe nucleus. Dose-response studies indicated that sensitivity to morphine's rewarding property was increased by substantia nigra lesions and decreased by medial raphe lesions. Lesions of the dorsal raphe nucleus and of the locus coeruleus had no effect on self-administration behavior. An interaction between ascending dopaminergic and serotonergic pathways appears to be involved in the mechanism of morphine reinforcement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00439102
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    In vivo sterol biosynthesis by pea aphid symbiotes as determined by digitonin and electron microscopic autoradiography (1977)
    Springer
    Cell & tissue research 176 (1977), S. 179-190 
    Details
    ISSN: 1432-0878
    Keywords: Cholesterol ; Symbiotes ; Aphids ; Digitonin ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pea aphid primary symbiotes have previously been shown to synthesize cholesterol in vitro. Two electron microscopic techniques were used here to determine whether the symbiotes also synthesize cholesterol in vivo and whether this cholesterol is made available to the aphid. We also inquired into a possible role of secondary symbiotes in cholesterol biosynthesis. Treatment of aphids with digitonin resulted in significant alteration of ultrastructural sites in primary and secondary symbiote membranes. We concluded that these sites are areas of high cholesterol concentration in the symbiotes. Electron microscopic autoradiography with 3H-mevalonate precursor indicated that both primary and secondary symbiotes synthesize cholesterol; in both cases, the majority of grains were associated with the symbiote membranes. While the frequency of grains on the symbiotes remained constant, irrespective of incubation time in labelled media, the frequency of grains over surrounding tissues increased exponentially as the time of incubation was increased from 30 min to 8 h, indicating that symbiote cholesterol is transported to other tissues. High voltage electron microscopic autoradiography permitted thick section autoradiography, reducing the time of emulsion exposure from 54 days (thin section) to 12 days (0.5 μm sections).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229461
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of dietary cholesterol on the pattern of osmium deposition in the symbiote-containing cells of the pea aphid (1977)
    Springer
    Cell & tissue research 176 (1977), S. 191-203 
    Details
    ISSN: 1432-0878
    Keywords: OsO4 ; Cholesterol ; Symbiotes ; Aphids ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pea aphids left for 48 h in unbuffered osmium tetroxide show heavy staining of many organelles in the symbiote-containing cells (mycetocytes and sheath), embryos and oenocytes very similar to that characteristic of mammalian sterol-synthesizing cells. However, the staining of the pea-aphid cells is, to a large extent, dependent on the presence of cholesterol benzoate, or free cholesterol, in the aphid's diet. In aphids cultured in vitro with 3H mevalonate in the presence of added cholesterol, the incorporation of label into the cholesterol and lanosterol fractions is significantly reduced. If the dietary cholesterol effects a similar inhibition in vivo, the cholesterol-dependent osmium staining could be due to precursors(s) of cholesterol accumulating in the intracellular sites described. There is also osmium staining of large (normally electron-transparent) vacuoles in mycetocytes, gut and fat body, irrespective of dietary cholesterol.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00229462
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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