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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 226 (1978), S. 363-368 
    ISSN: 1432-0711
    Keywords: Hysterectomy ; Ovarian function ; Premenopause ; Hormonal cycle ; Hysterektomie ; Ovarialfunktion ; Pramenopause ; Zyklus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 48 Frauen nach Hysterektomie im Alter von 28–43 Jahren wurden 5–10 Jahre später Plasmabestimmungen von FSH, LH, Östradiol-17β und Progesteron durchgeführt. Zum Vergleich diente eine Gruppe prämenopausaler Frauen mit fluktuierender FSH-Erhöhung und eine weitere mit stabilem Hypergonadotropismus. Es wurde festgestellt, daß nach Hysterektomie bei den Frauen unter 40 Jahren stets, zwischen 41 und 45 Jahren in drei Viertel und mit mehr als 46 Jahren in der Hälfte eine normogonadotrope und normosteroidale Ovarialfunktion vorlag. Die Frauen mit fluktuierendem oder stabilem Hypergonadotropismus waren jedoch nach Hysterektomie durchschnittlich um 2 Jahre jünger als die prämenopausalen Frauen mit entsprechender Ovarialfunktion. Eine gewisse zeitliche Vorverlegung von nachweisbaren Kriterien einer definitiven Ovarialinsuffizienz war bei einem Teil der Frauen damit nicht auszuschließen.
    Notes: Summary Plasma-FSH, -LH, -Estradiol-17β, and -Progesterone were determined weekly in women aged between 28 and 43 years who had been hysterectomized 5–10 years before. The endocrine parameters were compared with those of women with a normal cycle and two groups of premenopausal women, the one showing a fixed hypergonadotropic state, the other slightly elevated but still cyclic fluctuations of FSH and normal LH values. After hysterectomy, normal ovulatory cycles were found in all women of up to 40 years, in 75% of those between 41 and 45 years and in 50% of those beyond 46 years. The average age of women with fluctuating or fixed hypergonadotropism was 2 years less in the hysterectomiced group. Thus, a certain acceleration of ovarian insufficiency caused by hysterectomy cannot be denied.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Chromatographia 11 (1978), S. 257-259 
    ISSN: 1612-1112
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 113-114 
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 115-120 
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 321-326 
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 164-168 
    ISSN: 0935-6304
    Keywords: Thin Layer Chromatography, HPTLC ; Fastest possible analytical mode: Anticircular separation ; First principal analytical details ; Most economical TLC/HPTLC technique, quantitative comparison with linear and circular mode ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The principal analytical details for the third of three possible modes in high performance thin-layer chromatography are given, namely the anticircular mode. Separation is achieved by allowing the mobile phase to enter the plate layer on a precise outer circle line, from where it flows towards the centre with nearly constant speed. This technique is theoretically and practically the fastest of all three possible in HPTLC. It permits maximum sample capacity with a minimum of time, layer and mobile phase consumption. It is therefore the most economical HPTLC technique.A new carrier-free mobile phase transfer principle is used. The conditions for qualitative and quantitative analysis are good: repeatability, reproducibility and accuracy of routine TLC analyses are superior to those achieved by the classical trough technique. The specially narrow spot-path in anticircular HPTLC facilitates automated quantitation. Compared with the linear and circular modes, the anticircular mode shows better separation and significantly increased sensitivity at higher Rf-values. The drawback, however, is that the separation power (expressed by the separation number) is lower compared with the other two modes.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 201-202 
    ISSN: 0935-6304
    Keywords: Gas Chromatography ; Micropacked columns ; Series-coupled ; Polarity change by temperature variation ; Temperatures independently varied in each column ; Retention index data for study of microprocessor-controlled resolution optimization ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 9-9 
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 1 (1978), S. 297-299 
    ISSN: 0935-6304
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    New York : Wiley-Blackwell
    Biopolymers 17 (1978), S. 1927-1938 
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Somatostatin (SS) and two glucagon selective analogs [D-Cysl4]-SS and [D-Trp8, D-Cys14]-SS have been synthesized in gram quantities by the solid-phase procedure. A general modification of Monahan and Gilon's procedure for esterification of the first protected amino acid onto the chloromethylated resin as well as a general protocol for solid-phase peptide synthesis on Beckman 990 automatic synthesizer are described. A new general procedure for disulfide formation, which involves the adaptation of the “high-dilution” principle to the ferricyanide oxidation and the optimization of the sequence of purification steps as applied to somatostatin and its analogs, yields highly purified peptides (≥ 199% pure) as checked by reverse-phase high-pressure liquid chromatography - which is shown to be a highly sensitive, resolutive, and quantitative analytical tool for evaluation of the homogeneity of peptides.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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