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  • 1975-1979  (5)
  • 1860-1869
  • 1979  (5)
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Material
Years
  • 1975-1979  (5)
  • 1860-1869
Year
  • 1
    Electronic Resource
    Electronic Resource
    Dioxolenium ion trapping in the hydrolysis of cyclic ortho esters: the rate-determining step (1979)
    s.l. : American Chemical Society
    The @journal of organic chemistry 44 (1979), S. 619-622 
    Details
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jo01318a028
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Determination of nitrate and nitrite in whey powder (1979)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 27 (1979), S. 1277-1279 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf60226a043
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    GENETIC CONTROL OF THE IMMUNE RESPONSE TO MAMMALIAN CHYMOTRYPSINS IN MICEq (1979)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 6 (1979), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The immune response to the antigen bovine pancreatic α-chymotrypsin was investigated in ten recombinant strains of mice. Using a fixed antigen-percentage bound isotope technique, it was found that the quantity of antibody produced was related to the H-2 haplotype of the responding animal. A continuous distribution for the mean antibody responses was obtained for the ten strains of mice. High responsiveness was associated with the H-2 haplotype y2. The genetic control of the immune response to this immunogen was found to be both quantitative and qualitative.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1979.tb00676.x
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    GENETIC CONTROL OF THE IMMUNE RESPONSE TO MAMMALIAN CHYMOTRYPSINS IN MICE (1979)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 6 (1979), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The primary and secondary immune response to the antigen bovine pancreatic α-chymotrypsin was investigated in in inbred mice. It was found that strain differences in the immune response only became apparent after secondary immunization. The genetic control of the immune response was investigated in twelve different strains of mice, F1, F2 and F1 backcross hybrids, following secondary immunization. A continous distribution for the mean antibody responsiveness was obtained. High responsiveness was associated with both the H-2 haplotype and three non-H-2 loci. Furthermore the F1 hybrids produced a greater quantitative antibody response to chymotrypsin than either of the corresponding parental strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1979.tb00675.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Vindesine a review of phase-II trials (1979)
    Springer
    Cancer chemotherapy and pharmacology 2 (1979), S. 271-274 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Vindesine is a new vinca alkaloid with broadspectrum antineoplastic activity in experimental tumor models. Phase-I studies have shown that a weekly dosage regimen of 3–4 mg/m2 IV produces manageable toxicity, with leukopenia and peripheral neuropathy being dose-limiting. Two hundred seventy-five patients have been enlisted in Phase-II trials at the Memorial Sloan-Kettering Cancer Center. Major objective responses (complete and partial remissions) were seen in bronchogenic carcinomas, melanoma, testicular carcinoma, esophageal carcinoma, acute lymphocytic leukemia, malignant lymphoma (Hodgkin's and non-Hodgkin's) and Wilms' tumor. Patients with hematologic and germ cell neoplasms were treated on a daily administration schedule (1.0–1.3 mg/m2 IV for 5–7 days). Vindesine was well tolerated, with less than 5% of patients having a WBC nadir of〈1000 cells/mm3 and with a platelet-sparing effect noted. Dose-related peripheral neuropathy occurred frequently and was generally mild to moderate in degree. Vindesine appears to be an active agent whose role will be further defined by completion of ongoing trials.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257194
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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