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  • 1990-1994  (4)
  • 1980-1984  (4)
  • 1993  (4)
  • 1980  (4)
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  • 1990-1994  (4)
  • 1980-1984  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    The 70-kDa Heat Shock Cognate Protein (HSC70) Is a Major Constituent of the Central Nervous System and Is Up-Regulated Only at the mRNA Level in Acute Experimental Autoimmune Encephalomyelitis (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 61 (1993), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The expression of the 70-kDa heat shock cognate (HSC70) and stress-inducible (HSP70) proteins, and their mRNAs, was examined in experimental autoimmune encephalomyelitis, a model of inflammatory demyelination in the CNS. This study was undertaken as an extension of previous work demonstrating an abrupt decline in mRNA levels of both glial fibrillary acidic protein and the low-molecular-weight neurofilament subunit in experimental autoimmune encephalomyelitis spinal cord at 12 days after inoculation, the height of inflammation and clinical signs. Using the same total RNA preparations as our previous study, we report here that mRNA levels for HSC70 increased approximately sixfold over control values at the same time that glial fibrillary acidic protein and low-molecular-weight neurofilament subunit messages decreased and were similar to controls by 21 days after inoculation. In situ hybridization experiments showed that HSC70 mRNA was predominantly expressed in neurons and that the influx of inflammatory cells into the CNS was not responsible for the large increase in HSC70 message. Despite this elevation in mRNA, only small (if any) increases in protein levels for HSC70 were detected by both western blotting and in vitro cell-free translation systems. However, by quantitative immunoblotting, we determined that constitutive levels of HSC70 comprised a substantial portion of CNS proteins, representing 2–3% of the total protein content of spinal cord. Immunohistochemical staining illustrated that the distribution of HSC70 was consistent with that of its message. In contrast, no HSP70 mRNA or protein was detected in either control or experimental animals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1993.tb13627.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Serotypic Variation Among Isolates of Ichthyophthirius multifiliis Based on Immobilization (1993)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 40 (1993), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Efforts have been made to determine whether surface antigens could be used as biochemical markers to define strain differences in the parasitic ciliate Ichthyophthirius multifiliis. In previous studies, a wild-type isolate designated G1 was found to have surface proteins analogous to the immobilization antigens of Paramecium and Tetrahymena; rabbit antiserum against this strain immobilizes homologous cells in vitro. It has now been shown for two additional Ichthyophthirius isolates (designated G1.1 and G2) that immobilization antigens are both present and serologically distinct. Proteins of similar size, which cross-react in Western blots with rabbit antisera against immobilization antigens of the G1 strain, are nevertheless found in the G1.1 and G2 isolates. As shown by Southern blotting analysis, the G1.1 and G2 strains also contain genomic DNA sequences which hybridize with an immobilization antigen cDNA from G1 when probed under conditions of reduced stringency. The serotypic differences in immobilization between I. multifiliis isolates appear to be stable over time and provide a means of discriminating strains. In addition to providing a basis for comparative studies, the work described here has implications for the development of vaccines against this important fish parasite.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1993.tb04480.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    REPRODUCIBILITY OF BIPARIETAL DIAMETER MEASUREMENTS OBTAINED WITH A REAL-TIME SCANNER (1980)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 87 (1980), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In 80 patients, multiple measurements of the fetal biparietal diameter were made during one examination using a real-time scanner equipped with a coded cephalometer. From the sets of data, the means and standard deviations for the group of 80 patients were calculated. In 80 per cent of cases, the individual standard deviations of the results were less than or equal to the estimated standard deviation of the group as a whole. The variability of measurement related to biparietal diameter was least in the range 59 to 83 mm. Comparison of the results obtained with the coded device and others obtained ‘blind’ does not reveal any significant advantage for the coded device.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1980.tb04580.x
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    Paper (German National Licenses)
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  • 4
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    Unknown
    Vico in Context (1993)
    Newbury Park, Calif. : Periodicals Archive Online (PAO)
    Philosophy of the social sciences. 23:2 (1993:June) 243 
    Details
    ISSN: 0048-3931
    Topics: Philosophy , Sociology
    Notes: Review Essays
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:h310-1993-023-02-000006
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  • 5
    Electronic Resource
    Electronic Resource
    Juvenility and resistance of a superoxide tolerant plant to diseases and other stresses (1993)
    Springer
    Naturwissenschaften 80 (1993), S. 420-422 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01168338
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Relation of mantle conductivity to physical conditions in the asthenosphere (1980)
    Springer
    Surveys in geophysics 4 (1980), S. 43-55 
    Details
    ISSN: 1573-0956
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract Magnetotelluric soundings show that the conductivity increases in the asthenosphere. The depth of this conductivity zone decreases with an increase of the surface heat flow, i.e. in such cases the lithospheric plate is thinner. The depth of the velocity decrease of seismic shear wave (S waves) shows the same connection with the surface heat flow. The solidus of a mixed-volatile medium intersects the temperature curves belonging to different surface heat flows at depths where the conductivity increase and the velocity decrease appear. These connections point to partial melting in the asthenosphere, which can decrease the viscosity too, and help the movement of the lithospheric plates according to the ideas of global tectonics. The melt fraction of peridotite and pyrolite determined by Shankland and Waff from the effective conductivity of the asthenosphere is about 3–4% at 30 kbar and ato *=0.1 S m−1. In the upper mantle of old shields it is likely that there is no well-developed asthenosphere due to the low temperature. Over these so-called ‘viscous anchors’ the lithospheric plates do not move. It is supposed that the conductivity increases observed below crystalline shields at a depth of about 300 km indicate the phase transition of rocks. Thus in these areas the surface of the phase transition can be at a higher position than in the younger tectonic units.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01452957
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Congenital deficiency in plasma kallikrein and kininogens in the brown Norway rat (1980)
    Springer
    Cellular and molecular life sciences 36 (1980), S. 586-587 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The kallikrein-kininogens-kinins system has been investigated in the brown Norway rat. In this breed the stores of kininogens in the plasma are reduced and the plasma kallikrein-like activity appears to be absent both in vivo and in vitro.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01965817
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Book review (1980)
    Springer
    Periodica mathematica Hungarica 11 (1980), S. 87-87 
    Details
    ISSN: 1588-2829
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02019987
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    Paper (German National Licenses)
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