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  • 1
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    Provincetown, Mass., etc. : Periodicals Archive Online (PAO)
    The Journal of Genetic Psychology. 137:1 (1980:Sept.) 125 
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  • 2
    ISSN: 1432-1440
    Keywords: Acute myocardial infarction ; Plasma T3, rT3, T4, TSH ; Akuter Myocardinfarkt ; T3, rT3, T4 und TSH im Plasma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird über das Verhalten der Schilddrüsenhormone und des TSH im Plasma von Männern im Frühstadium eines akuten Myocardinfarktes berichtet. T3 war bereits bei Klinikaufnahme erniedrigt und fiel weiter rapide ab. rT3 war bei Klinikaufnahme erhöht und erreichte nach 19 Stunden sein Maximum. T4 und TSH zeigten keine wesentlichen Veränderungen. Die Ergebnisse deuten daraufhin, daß es in der Frühphase des Myocardinfarktes zu einer raschen Verschiebung der Monodejodination des T4 zugunsten von rT3 anstelle von T3 mit rapidem. Abfall des T3 und Anstieg des rT3 im Blut kommt.
    Notes: Summary The changes of thyroid hormones and TSH in plasma of males in the early stage of myocardial infarction are described. Already on admission T3 was diminished and went on falling. On admission rT3 was elevated and reached its maximum after 19 hours. T4 and TSH did not show essential alterations. The results suggest that in the early stage of myocardial infarction a rapid shift of the monodeiodination of T4 to rT3 occurs instead of T3 with a quick decrease of T3 and increase of rT3 in the blood.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Journal of cancer research and clinical oncology 96 (1980), S. 65-78 
    ISSN: 1432-1335
    Keywords: Ehrlich ascites tumor ; Proliferation kinetics ; Partial synchronization ; Combination chemotherapy ; Cytostatic drugs ; Adriamycin ; Hydroxyurea ; Vincristine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This paper deals with experimental investigations concerning the composition of a cytostatic three-drug-protocol in diploid Ehrlich-Ascites-Tumor (EAT) cells in vivo at a far advanced stage of the disease. Hydroxyurea (HU) and vincristine (VCR) were used in very low doses to induce a modification of the growth pattern of tumor cells alike partial synchronization. Adriamycin (ADM) was selected as cytocidal drug during DNA synthesis of the partially synchronized cells. It was found that the sequential combination of HU and VCR (first HU and 12h thereafter VCR) caused the greatest alteration of growth pattern compared with other combination protocols. A further statistically significant increase of the degree of synchrony was observed after a second VCR administration—22 h after HU. By means of this protocol the EAT was subdivided into two proliferating subpopulations, a diploid and a tetraploid one. the tetraploid population resulted from surviving cells being not able to perform cytokinesis correctly, so that polynuclear cells and cells with a large single nucleus containing tetraploid DNA values were created. With respect to therapy, the administration of ADM at the time of DNA synthesis of the partially synchronized cells resulted in a statistically significant prolongation of the mean survival time and in 30% of cures of the animals. The dosage of ADM was 2.6 mg/kg, i.e., a nonlethal dose (50% of the LD10). Other combinations, i.e., simultaneous or reversed sequential combinations, did not show any therapeutic improvement compared to single drug therapy of ADM.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 352 (1980), S. 525-525 
    ISSN: 1435-2451
    Keywords: Gastric transformation surgery ; Gastric motor activity ; Gastric emptying rate ; Magenumwandlungsoperation ; Motorische Magenfunktion ; Magenentleerung ; Duodenogastraler Reflux
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit einer breiförmigen Formeldiät und Tc-99m-DTPA als Tracer wurde die Magenentleerung bei 26 Patienten nach Magenumwandlungsoperation (Billroth II in Billroth I) gemessen. Die Methode war geeignet, gleichzeitig einen duodenogastralen Reflux darzustellen. Bis zur 46 min war die Entleerungskurve für den Gesamtmagen von derjenigen der Kontrollgruppe (11 Magengesunde) verschieden. Vor allem ließ sich eine rasche Anfangsentleerung erkennen. Eine eindeutige Korrelation zwischen nuklearmedizinisch registrierten Entleerungsstörungen und subjektiven Symptomen fand sich nicht.
    Notes: Summary Gastric emptying was measured, using99mTc-DTPA as the tracer, in 26 patients receiving a mashed formula diet after transformation surgery (Billroth II to Billroth I). This method was also suitable in demonstrating duodenogastric reflux. Up to 46 min, the gastric emptying rate, particularly that observed initially, was significantly higher compared with that in normal patients. There was no obvious correlation between disturbances in gastric emptying determined by this radionuclear method and subjective symptoms (dumping, food and biliary vomiting).
    Type of Medium: Electronic Resource
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