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  • 1980-1984  (5)
  • 1920-1924
  • 1981  (5)
  • Chemistry  (4)
  • Betablocker  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 230 (1981), S. 231-237 
    ISSN: 1432-0711
    Keywords: Fenoterol-Tokolyse ; Tachykardie ; Betablocker ; Antagonisierung ; Tocolysis ; Betamimetic ; Tachycardia ; Betalytic ; Antagonism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary None of the betamimetics have an exclusively tocolytic effet. By stimulating the cardiovascular β-receptor, they also cause a substantial increase in the heart rate and a decrease in blood pressure. We administered 4–5 μg/min of Fenoterol to 13 patients during the first stage of labour. This led to complete inhibition of labour. To reduce cardiac side effects, a primarily cardiac β-blocker (5 mg Atenolol or 20 mg Metoprolol) was also given. The maternal and fetal heart rates were measured by ECG and by fetal scalp-electrode, respectively. The fetal heart rate remained largely unchanged, both during the Fenoterol infusion as well as during the additional administration of the β-blocker. The maternal heart rate, which increased under the influence of the Fenoterol, fell (p ≤ 0.01) but did not return to normal. In all cases the β-blockade led to a brief increase in uterine activity.
    Notes: Zusammenfassung Neben dem tokolytischen Effekt verursachen Betasympathikomimetika eine erhebliche Steigerung der Herzfrequenz und eine Blutdruckerniedrigung durch Stimulation der kardialen und vaskulären Betarezeptoren. Dreizehn Patienten erhielten während der Eröffnungsperiode 4–5 μg/min Fenoterol i.v. Nach vollständiger Wehenhemmung wurde wegen der unerwünschten Kreislaufreaktionen zusätzlich ein Betablocker mit vorwiegend kardialer Wirkung (Atenolol 5 mg oder Metoprolol 20 mg) verabreicht. Die Registrierung der Herzfrequenzen erfolgte über mütterliches EKG und fetale Skalpelektrode. Sowohl während der Fenoterol-Infusion als auch während der zusätzlichen Verabreichung des Betablockers änderte sich die fetale Herzfrequenz nur unwesentlich. Die Fenoterol-bedingte mütterliche Tachykardie konnte gesenkt (p ≦ 0,01), aber nicht vollständig aufgehoben werden. In allen Fällen führte die Betablockade zu einer kurzzeitigen Steigerung der Uterusaktivität.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 20 (1981), S. 104-104 
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Angewandte Chemie International Edition in English 20 (1981), S. 109-109 
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 473 (1981), S. 85-90 
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Carbosilylated phospha-alkenesLithium-tris-trimethylsilylmethanide, (Me3Si)3C-Li, reacts with various organodichlorophosphines to give tris-(trimethylsilyl)-methyl-organochlorophosphines, the termal treatment of which under elimination of trimethylchlorosilane results in formation of the title compounds of the general formula B.NMR-data as well as the synthesis of compounds A and B will be discussed.
    Notes: Lithium-tris-trimethylsilylmethanid, (Me3Si)3C-Li, reagiert mit verschieden substituierten Organyldichlorphosphinen zur Tris-Trimethylsilylmethyl-organylchlorphosphinen A, deren thermische Beanspruchung unter Abspaltung von Trimethylchlorsilan zu den Titelverbindungen der allgemeinen Formel B führt.Die NMR-spektroskopischen Daten der Verbindungen des Typs A und B sowie deren Synthese wer-den diskntiert.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
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