ISSN:
1573-7217
Keywords:
breast cancer
;
estrogen receptors
;
steroid biosynthesis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The capacity of breast cancer to synthesise active androgens and estrogens has been related to estrogen receptor (ER) status in 79 postmenopausal patients with breast cancer. Although there was no quantitative relationship between levels of ER and steroid metabolism in ER positive tumours, there was (a) a positive correlation between estrogen synthesis and ER positivity and (b) increased androgen synthesis and ER negativity. This may imply an inherent difference in the handling of hormones in ER positive and negative tumours.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01806266
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