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  • 1980-1984  (4)
  • 1981  (4)
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  • 1980-1984  (4)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Virulent and Avirulent Strains of Babesia bovis: The Relationship Between Parasite Protease Content and Pathophysiological Effect of the Strain (1981)
    Oxford, UK : Blackwell Publishing Ltd
    The @journal of eukaryotic microbiology 28 (1981), S. 0 
    Details
    ISSN: 1550-7408
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A virulent strain of Babesia bovis (“L” strain) was rendered avirulent by irradiation with 35 krads with a γ source. Another virulent strain of B. bovis (“C” strain) was made avirulent by rapid blood passage through 12 splenectomised calves. Both the parent virulent and their respective avirulent strains were injected into susceptible cattle. A nonfatal disease was observed in those intact cattle that had avirulent parasites; however, a fatal disease was produced in those animals that had received virulent parasites and in splenectomised calves that had received avirulent parasites. Blood kinin levels rose and plasma kininogen levels fell significantly in those animals infected with both virulent strains. Nonsignificant changes occurred with these parameters in animals infected with avirulent parasites. Preparations of disrupted parasites were obtained from the four parasite populations. Both virulent strains contained high levels of protease. The avirulent forms contained insignificant amounts. As parasite doubling times and maximum parasitaemias were the same for all four parasite populations, we conclude that these enzymes are not obligatory for parasite multiplication in the vertebrate host. Their role in producing pathological changes in the host is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1550-7408.1981.tb02815.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The use of pathophysiological reactions to assess the efficacy of the immune response toBabesia bovis in cattle (1981)
    Springer
    Parasitology research 66 (1981), S. 41-48 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract A group of five splenectomised calves was immunised with a soluble extract prepared from erythrocytes infected withBabesia bovis and then challenged by the intravenous inoculation of virulentB. bovis along with appropriate control animals. All controls died but four of the five immunised animals survived. All survivors showed significantly lower activation of the coagulation and kinin systems and did not develop the hypotensive shock syndrome characteristic of acuteB. bovis infection. It was concluded that the concentrations of fibrinogen, kininogen, and bradykinin, and the production of soluble fibrin, cryofibrinogen, and high molecular weight fibrinogen complexes were useful criteria on which to assess the efficacy of the immune response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00941944
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    AcuteBabesia bovis infections: Plasma creatine kinase, lactate dehydrogenase and creatinine levels and associated muscle damage (1981)
    Springer
    Parasitology research 64 (1981), S. 297-302 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Two groups of five two-year-old Hereford steers were infected with two virulent strains ofB. bovis. The plasma concentrations of creatine kinase (CK), lactate dehydrogenase (LDH), and creatinine rose early in infection and showed highly significant increases terminally. Extensive skeletal muscle degeneration was observed terminally as was degeneration of myocardium, although this was much less extensive. Terminal clinical signs included posterior muscle wasting, weakness, and recumbency. It was concluded that the extensive changes to muscle and to CK and LDH were caused by anoxia due primarily to shock and stasis of the circulation induced by the parasites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00927377
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Babesia bovis (Argentina): Studies of plasma lipids and lipoproteins during acute infections in cattle (1981)
    Springer
    Parasitology research 65 (1981), S. 271-276 
    Details
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Preliminary studies have demonstrated changes to the lipid metabolism of cattle acutely infected withBabesia bovis. Total lipid, total cholesterol, and phospholipids decreased significantly during infection. Associated with this was a decrease in concentration of serum lipoproteins and a loss of their electrophoretic heterogeneity. These changes are discussed in relation to the pathophysiological changes during infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00926720
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    Paper (German National Licenses)
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