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  • 1985-1989  (4)
  • 1980-1984  (4)
  • 1975-1979
  • 1935-1939
  • 1987  (4)
  • 1982  (4)
  • 1
    Electronic Resource
    Electronic Resource
    Antiallergic activity of loratadine, a non-sedating antihistamine (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 42 (1987), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Loratadine is a new non-sedating antihistamine. The present studies compared loratadine and terfenadine, another non-sedating antihistamine, for their ability to inhibit the bronchial response to histamine and other autacoids which have been implicated as contributing to the symptoms of an allergic reaction. In addition, the two antihistamines were evaluated in models of immunologically mediated allergic reactions. Loratadine is a more potent inhibitor of histamine-induced bronchospasm in guinea pigs than is terfenadine. Both antihistamines exhibit marked antiserotonin activity at doses 10 times their antihistamine ED50 values. In contrast, loratadine and terfenadine produce little or no inhibition of the bronchial responses to methacholine, leukotriene C4 or platelet-activating factor. An allergic bronchospasm in guinea pigs is inhibited by loratadine (ED50= 0.40 mg/kg, p.o.) and terfenadine (ED50= 1.7 mg/kg, p.o.). The bronchospasm associated with allergic anaphylaxis in rats is significantly inhibited by 10 mg/kg, p.o. loratadine and 30 mg/kg, p.o. terfenadine. Loratadine exhibits antiallergy activity in vitro. At micromolar concentrations, loratadine inhibits the release of histamine from Con A and A23187-stimulated rat peritoneal mast cells and the release of histamine and leukotrine C4 from a Con A-stimulated cloned murine mast cell line
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1987.tb02188.x
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  • 2
    Electronic Resource
    Electronic Resource
    Topical tropical entomology from Africa (1982)
    [s.l.] : Nature Publishing Group
    Nature 299 (1982), S. 507-507 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Insect Science and Its Application. Editor Thomas R.Odhiambo. 4/yr. (Pergamon.) £42.50, $48.57. NOT content with founding the International Centre for Insect Physiology and Ecology (ICIPE) in Nairobi, Professor Odhiambo has now started the first international entomological journal to ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/299507a0
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  • 3
    Electronic Resource
    Electronic Resource
    Hepatic iron stores and markers of iron overload in alcoholics and patients with idiopathic hemochromatosis (1982)
    Springer
    Digestive diseases and sciences 27 (1982), S. 909-916 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Liver iron concentrations were determined in 60 alcoholics with liver disease of varying severity, 15 patients with untreated idiopathic hemochromatosis, and 16 control subjects with biliary tract disease. Mean liver iron concentrations (μg/100 mg dry weight) were significantly greater in the alcoholics (156.4±7.8 (sem);P〈0.05) and in patients with idiopathic hemochromatosis (2094.5±230.7;P〈0.01) than in control subjects (53.0±7.0). Liver iron concentrations of 〉140 μg/100 mg were found in 17 alcoholics (29%) and in all 15 patients with idiopathic hemochromatosis. Liver iron concentrations 〉1000 μg/100 mg were found in all patients with idiopathic hemochromatosis but in none of the alcoholics. In the alcoholics no relationship existed between liver iron concentrations and the amount of alcohol consumed daily, the length of the drinking history, the amount of beverage iron consumed daily, or the severity of the liver disease. Serum ferritin concentrations reflected iron stores in patients with hemochromatosis and in alcoholics with minimal liver disease. However, in alcoholics with significant liver disease serum ferritin concentrations did not reflect iron stores accurately, although with normal values iron overload is unlikely. Serum iron concentration and percentage saturation of total iron-binding capacity were of little value in assessing iron status in either alcoholics or patients with hemochromatosis. Measurement of the liver iron concentration clearly differentiates between alcoholics with significant siderosis and patients with idiopathic hemochromatosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01316575
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  • 4
    Electronic Resource
    Electronic Resource
    Serum ferritin and binding of serum ferritin to concanavalin A as a tumor marker in patients with primary liver cell cancer and chronic liver disease (1982)
    Springer
    Digestive diseases and sciences 27 (1982), S. 111-116 
    Details
    ISSN: 1573-2568
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Total ferritin concentration was measured in sera of 30 patients with primary liver cell cancer (PLCC) and 33 patients with cirrhosis and compared with serum alpha-fetoprotein levels as a diagnostic marker of PLCC. Serum ferritin concentration was raised in 19 patients (63%) with PLCC and 11 patients (33%) with cirrhosis. The median level was significantly higher (P〈0.001) in the PLCC group (560 μg/liter) than in the cirrhotic group (137 μg/liter), although there was considerable overlap. Serum ferritin was posititively correlated with serum aminotransferase levels in the cirrhotic patients (r=0.53,P〈0.001), reflecting hepatic necrosis, but not in the PLCC patients. The concentration of ferritin binding to concanavalin A was measured in the sera of patients with elevated total serum ferritin. Although the proportion of bound ferritin was decreased in the majority of PLCC sera compared to controls (P〈0.001), there was overlap with the cirrhotic group, making it unlikely that this assay is useful in distinguishing a tumor-specific isoferritin. Serum alpha-fetoprotein levels were elevated in 21 patients (70%) with PLCC and proved to be a highly sensitive and specific test for PLCC. There was no relationship between the alpha-fetoprotein and serum ferritin concentrations. Serum ferritin is inferior to alpha-fetoprotein as an initial screening test for PLCC, but in alpha-fetoprotein-negative patients serum ferritin may have a role in monitoring therapy. Patients with cirrhosis with normal serum alpha-fetoprotein and ferritin concentrations are very unlikely to have PLCC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01311703
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  • 5
    Electronic Resource
    Electronic Resource
    Secretion and membrane recycling in plant cells: novel intermediary structures visualized in ultrarapidly frozen sycamore and carrot suspension-culture cells (1987)
    Springer
    Planta 171 (1987), S. 43-57 
    Details
    ISSN: 1432-2048
    Keywords: Acer ; Daucus ; Cell culture ; Freeze-fracture (rapid freezing) ; Membrane recycling ; Plasma membrane ; Secretion (vesicle-mediated)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Freeze-fracture electron microscopy of propane-jet-frozen samples has been employed to investigate vesicle-mediated secretion and membrane recycling events in carrot (Daucus carota L.) and sycamore maple (Acer pseudoplatanus L.) suspension-culture cells. Stabilization of the cells by means of ultrarapid freezing has enabled us to preserve the cells in a turgid state and to visualize new intermediate membrane configurations related to these events. Indeed, many of the observed membrane configurations, such as flattened membrane vesicles with slit-shaped membrane fusion sites and horseshoe-shaped membrane infoldings, appear to result from the action of turgor forces on the plasma membrane. Individual cells exhibited great variations in numbers and types of membrane configurations postulated to be related to secretion and membrane-recycling events. In the majority of cells, the different membrane profiles displayed a patchy distribution, and within each patch the membrane configurations tended to be of the same stage. This result indicates that secretory events are triggered in domains measuring from 0.1 to about 10 μm in diameter. Based on an extensive analysis of the different membrane configurations seen in our samples, we have formulated the following model of vesicle-mediated secretion in plant cells: Fusion of a secretory vesicle with the plasma membrane leads to the formation of a single, narrow-necked pore that increases in diameter up to about 60 nm. During discharge, the vesicle is flattened, forming a disc-shaped structure perpendicular to the plane of the plasma membrane. As the vesicle is flattened, the pore is converted to a slit, the maximum length of which coincides with the diameter of the flattened vesicle. The flattened vesicle then tips over and concomitantly the plasma-membrane slit becomes curved into a horseshoe-shaped configuration as it extends along the outer margins of the tipped-over vesicle. Some coated pits are present interspersed between the above-mentioned structures, but their numbers appear insufficient to account for an exclusively endocytotic mechanism of membrane recycling. Instead, our micrographs are more consistent with a mixed mode of recycling of membrane components to the cortical endoplamic reticulum and to Golgi cisternae that involves both internalization of membrane by endocytosis and of individual lippid molecules by unknown mechanisms (lipid exchange proteins?). To this end, overall flattening out of the horseshoe-shaped membrane infoldings is accompanied by a retraction and reduction in size of their central, tongue-like structure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395066
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  • 6
    Electronic Resource
    Electronic Resource
    Ethyl nicotinate (1982)
    Springer
    Journal of chemical ecology 8 (1982), S. 1299-1303 
    Details
    ISSN: 1573-1561
    Keywords: Thrips obscuratus ; Thysanoptera ; Thripidae ; attractant ; ethyl nicotinate ; apricots ; peaches
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Ethyl nicotinate was found to be a potent attractant forThrips obscuratus in peaches and apricots. The male-to-female ratio in traps was 1∶8. The chemical was more attractive than ripe fruit, with peak catches at harvest. Season-long trapping showed the efficiency of the chemical compared to unbaited traps. The chemical remained attractive for at least 2 weeks when 50 μl were placed in open 2-ml vial caps. Various pyralids, geometrids (Lepidoptera), and chironomids (Diptera) were also attracted in low numbers to ethyl nicotinate.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00987763
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  • 7
    Electronic Resource
    Electronic Resource
    Search for superdeformation in180Os (1987)
    Springer
    The European physical journal 328 (1987), S. 379-380 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Two-dimensional γ-ray energy correlations have been measured at high spins in1800s with the TESSA2 spectrometer. The Eγ − Eγcorrelation matrix displays ridges characteristic of rotational bands with different energy separations of 96± and 72± keV for the energy regions of 660 to 840 keV and 975 to 1170 keV, respectively. The separation of these ridges remains constant in both energy regions. The dynamical moments of inertia are θ(2) =83±3 and 111±5 ħ2/MeV, respectively. The latter value suggests superdeformation in1800s with an axis ratio c/a=1.76 (β2 ≅0.64) at high spins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01290507
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  • 8
    Electronic Resource
    Electronic Resource
    Functional response of pacific damsel bug,Nabis kinbergii [Hemiptera: Nabidae] (1987)
    Springer
    BioControl 32 (1987), S. 303-309 
    Details
    ISSN: 1573-8248
    Keywords: Pacific damsel bug ; nabid ; functional response ; Punaise du Pacifique ; nabide ; réponse fonctionnelle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Résumé La punaise,Nabis kinbergii Reuter est rencontrée communément dans les champs de luzerne à la fin de l'été et durant l'automne en Nouvelle Zélande. Son potentiel en tant que prédateur des espèces communes d'insectes ravageurs n'a pas encore été étudié. Ce travail rend compte de la roponse fonctionnelle des femelles adultes et des 5e stades larvaires de cette punaise vis-à-vis de deux espèces proies, le miride:Sidnia kinbergi (Stal) et le puceron du pois:Acyrtosiphon pisum (Harris). Une équation deHolling (1959) de type II définit bien la réponse fonctionnelle de ce prédateur sauf lorsque les 5e stades n'ont que des nymphes du Miride pour proie. Cette punaise,Nabis kinbergii manifeste des réponses identiques à celles d'un autreNabidae: Reduviolus americoferus (L.).
    Notes: Abstract The functional responses of adult and 5th instar Pacific damsel bug,Nabis kinbergii Reuter were determined under laboratory conditions using Australian crop mirid,Sidnia kinbergi (Stal), and pea aphid,Acyrthosiphon pisum (Harris) as prey.Holling's (1959) type II equation was found to adequately define the functional response of this predator except when 5th instar nymphs were provided with Australian crop mirid as prey. In this instance, a type III response was found.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02373255
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