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  • 2000-2004  (3)
  • 1990-1994
  • 1980-1984  (1)
  • 2000  (3)
  • 1983  (1)
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  • 2000-2004  (3)
  • 1990-1994
  • 1980-1984  (1)
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  • 1
    Electronic Resource
    Electronic Resource
    Tufted angioma (angioblastoma): case report and review of 41 cases in the Japanese literature (2000)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 25 (2000), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a 53-year-old man with a 2-year history of a violaceous indurated plaque on the shoulder. Although angiosarcoma was clinically suspected, histological examination revealed numerous lobules (‘tufts’) with cleft-like vascular lumina throughout the dermis and subcutaneous tissue. Tumour cells had no nuclear atypia and were positive for CD34, but almost negative for factor VIII-related antigen. These findings were compatible with a diagnosis of tufted angioma, or angioblastoma. We reviewed 41 cases reported in Japan and found that, although most patients presented during the first year of life (23/41), the condition does occur throughout childhood and adult life. Both sexes are affected equally and, contrary to some reports, it is unlikely that oestrogens have a pathogenic role.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2000.00724.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The effect of ultraviolet B irradiation on nitric oxide synthase expression in murine keratinocytes (2000)
    Copenhagen : Munksgaard International Publishers
    Experimental dermatology 9 (2000), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Nitric oxide (NO), which has several physiological functions in skin, is generated by NO synthase (NOS). NOS has at least three isoforms; endothelial NOS (eNOS), brain NOS (bNOS), and inducible NOS (iNOS). Ultraviolet B (UVB) irradiation has been reported to stimulate NO production in skin via induction or activation of NOS, however, the exact mechanism of NOS induction by UVB irradiation remains obscure. In this study, we investigated the direct effect of UVB on the expression of NOS isoforms in murine keratinocytes, and found a significant increase in NO production within 48 h. mRNA and protein expressions of bNOS were both enhanced by UVB irradiation in murine keratinocytes, whereas iNOS mRNA expression was suppressed at 4 and 12 h after UVB irradiation. These results suggest that the enhancement of NO production observed after UVB irradiation in murine keratinocytes may be explained in part by the upregulation of bNOS expression, but not iNOS expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0625.2000.009006417.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Allelic loss at the PTCH gene locus in jaw cysts but not in palmar pits in patients with basal cell nevus syndrome (2000)
    Springer
    Archives of dermatological research 292 (2000), S. 475-476 
    Details
    ISSN: 1432-069X
    Keywords: Key words Basal cell nevus syndrome ; PTCH gene ; Allelic loss ; Palmar pit ; Jaw cyst
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004030000154
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Plasma steroid levels and clinical effects after topical application of betamethasone (1983)
    Springer
    Graefe's archive for clinical and experimental ophthalmology 220 (1983), S. 209-214 
    Details
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A study was made of 41 patients (45 eyes) with post-operative irritative conditions to evaluate the clinical efficacy of topical betamethasone (BM) at various concentrations. The results obtained were as follows. First, serum concentrations of BM after treatment with 0.01% and 0.05% BM solution were much lower than those found after a 0.1% solution had been applied. However, no reduction in the serum cortisol was observed in the former. Second, the clinical evaluation was made in patients after cataract extraction. Marked and moderate improvement of post-operative inflammatory changes was observed in 90% of the patients treated with 0.05% and 0.1% solution and in only 30% of those treated with 0.01% solution. This study clearly shows the efficiency of 0.05% solution of BM with minimal suppressive effects on adrenal function.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02308076
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    Paper (German National Licenses)
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