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  • 1
    Electronic Resource
    Electronic Resource
    Distribution of acetylcholine-sensitivity in frog slow muscle fibres (1983)
    Springer
    Pflügers Archiv 397 (1983), S. 300-305 
    Details
    ISSN: 1432-2013
    Keywords: Slow muscle fibres ; ACh ; Sensitivity ; Distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract 1) The distribution of acetylcholine-sensitive membrane areas in slow muscle fibres of pyriformis muscles of Rana temporaria was examined by iontophoretic application of acetylcholine from high resistance pipettes. 2) ACh-sensitivity varied considerably along individual slow fibres and from fibre to fibre. In some fibres the sensitivity was restricted to segments of less than 100 μm, in others it was continuous over several millimeter. Segments of variable length, but up to several millimeter, were completely insensitive to acetylcholine. Highly sensitive spots (〉1,000 mV/nC) were found occasionally, their diameter being of the order of 10–20 μm only. The occurrence at rather regular intervals of ACh-sensitive areas was a rare observation; no evidence was found for a generalized ACh-sensitivity. 3) There were marked differences in the lengths of ACh-sensitive segments between surface fibres and fibres located in deeper layers of the muscles. 4) It is concluded that the ACh-sensitive membrane areas correspond to individual nerve muscle contacts of the small motor system whose spatial distribution is extremely variable. In superficial slow fibres the synaptic contacts seem to be located predominantly on the internal circumference of the fibres.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00580265
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  • 2
    Electronic Resource
    Electronic Resource
    Water permeability of periderm membranes isolated enzymatically from potato tubers (Solanum tuberosum L.) (1983)
    Springer
    Planta 158 (1983), S. 294-301 
    Details
    ISSN: 1432-2048
    Keywords: Periderm membranes ; Solanum, periderm ; Suberin ; Tuber ; Water permeability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The fine structure and water permeability of potato tuber periderm have been studied. Periderm membranes (PM) were isolated enzymatically using pectinase and cellulase. They were composed of, about six layers of phellem cells arranged in radial rows. The walls of phellem cells consist of cellulosic primary and tertiary walls and suberized secondary walls which are lamellated. Middle lamellae and primary walls contain lignin. Since the PM did not disintegrate during enzymatic isolation it appears that lignin also extends into the secondary suberized walls. The water permeability of PM was low, ranging from 1–3·10-10 m s-1. This low water permeability developed only during storage of tubers in air. Periderm membranes from freshly harvested tubers had a relatively high permeability. The low permeability of PM from stored tubers is attributed to soluble lipids associated with suberin since: (1) extraction of soluble lipids from PM increased permeability by more than 100-fold, (2) a phase transition of soluble lipids was observed between 46 and 51° C, and (3) only the permeability of PM decreased during storage while the permeability of extracted PM remained unchanged. Evidence is presented that two pathways for water movement exist in parallel. Pathway 1 is represented by middle lamellae and primary walls extending in radial direction across the membranes. This pathway has a relatively high specific permeability. Pathway 2 is represented by a polylaminated structure made up of tangential walls of phellem cells which are orientated normal to the direction of water flow. This pathway has a low specific permeability because of the properties of secondary walls incrusted with soluble lipids. It is calculated that about 10% of the water flows across pathway 1 and 90% across pathway 2 which has a volume fraction of 0.995.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00397330
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  • 3
    Electronic Resource
    Electronic Resource
    The pathogenesis of trypanosomiasis of the CNS (1983)
    Springer
    Virchows Archiv 399 (1983), S. 333-343 
    Details
    ISSN: 1432-2307
    Keywords: African trypanosomiasis ; Involvement of CNS ; Pathogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Parasitological examinations of the cerebrospinal fluid of 20 vervet monkeys (Cercopithecus aethiops), that had been infected with Trypanosoma rhodesiense, revealed that the CSF was regularly infested with trypanosomes in the early phase of the disease, at the earliest on the 13th day, in most of the animals in the 3rd or 4th week, after infection. Follow-up examinations of the CSF during the further course of the disease also regularly proved positive for trypanosomes. Histological studies in the animals that died at a mean of 65 days after infection (range 35 to 107 days) revealed encephalitis in the animal with the longest course of the disease. In all the other animals, meningitis alone was found. This was accompanied by a modified early encephalitic reaction, characterized by lympho-plasma-cellular infiltrates exclusively in the adventitial sheaths of those blood vessels passing into the brain from the leptomeninges affected by inflammatory infiltration. The early encephalitic reaction is interpreted as the morphological manifestation of an infestation of the perivascular spaces (Virchow-Robin spaces) with parasites. It indicates that CSF parasitosis in the early phase represents the point of departure for the encephalitis that develops in the late phase of the disease, and that the encephalitis presumably develops as a result of the migration of the trypanosomes out of the subarachnoid space into the perivascular spaces, and from there into the brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00612951
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  • 4
    Electronic Resource
    Electronic Resource
    Experiments on dynamical magnetic neutron diffraction by DyFeO3 (1983)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 39 (1983), S. 682-685 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The integrated reflecting powers of two nuclear and one magnetic reflexions of a DyFeO3 crystal have been measured. The results indicate that dynamical magnetic diffraction occurs. In addition, the integrated reflecting power of the magnetic reflexion was measured as a function of the magnetic field applied to the crystal, The results are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767383001385
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  • 5
    Electronic Resource
    Electronic Resource
    Theoretical investigations of the dynamical neutron diffraction by magnetic single crystals (1983)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 39 (1983), S. 679-682 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The fundamental equations for dynamical magnetic neutron diffraction including an external magnetic field are given. The reflecting power is calculated for some special cases for asymmetrical Laue geometry. Some Pendellösung effects are discussed. Analytical and numerical results for the integrated reflecting power are presented
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767383001373
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  • 6
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    Monika Leske u. a.: Warum es sich lohnt, um Begriffe zu streiten (Book Review) (1983)
    Berlin : Periodicals Archive Online (PAO)
    Deutsche Zeitschrift für Philosophie. 31:4 (1983) 503 
    Details
    ISSN: 0012-1045
    Topics: Philosophy
    Notes: REZENSIONEN
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4085-1983-031-04-000016
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  • 7
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    Rita Schober: Abbild - Sinnbild - Wertung (Book Review) (1983)
    Berlin : Periodicals Archive Online (PAO)
    Deutsche Zeitschrift für Philosophie. 31:7 (1983) 885 
    Details
    ISSN: 0012-1045
    Topics: Philosophy
    Description / Table of Contents: REZENSIONEN
    Notes: Zum 17. Weltkongress für Philosophie Montreal, Kanada, 21.-27. August 1983
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4085-1983-031-07-000016
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  • 8
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    Sinnstiftender Wert und Arbeitsleistung (1983)
    Berlin : Periodicals Archive Online (PAO)
    Deutsche Zeitschrift für Philosophie. 31:9 (1983) 1081 
    Details
    ISSN: 0012-1045
    Topics: Philosophy
    Notes: DISKUSSION
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:4085-1983-031-09-000009
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  • 9
    Electronic Resource
    Electronic Resource
    Einfluß des natürlichen Isotopengehaltes von Nährstoffen auf den Untergrund bei13C-Atemtests (1983)
    Springer
    European journal of nutrition 22 (1983), S. 107-115 
    Details
    ISSN: 1436-6215
    Keywords: 13C-Atemtest ; natürlicher Isotopengehalt von Nahrungsmitteln ; 13CO2-Gehalt der Atemluft ; parenterale Ernährung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary The long-term variation of the mean δ13C-value of breath-CO2 of Europeans (base value −26‰) was ±1‰ over a period of several months. However, the ingestion of products from corn, a C4-plant, caused remarkably higher shifts. In a fasted state and during rest a stability of the base value of ±0.3‰ could be attained for several hours. Longer fasting periods imply a shift of the CO2-δ-value due to the metabolism of body products. — By a change of the main energy source to corn products the δ13C-base line could be shifted to −18‰ within one day. After this shift even the metabolism of products from C3-plants could be investigated. The degradation curve and the integral degradation of fats were largely dependent on the method of application, and the base value largely interfered with the results. The period of maximum disintegration for a naturally and uniformly labelled fat was different from that of an artificially labelled trilinoleate. The results shall be used for the adjustment and the correction of the base line in13C-breath tests, especially with patients under parenteral nutrition.
    Notes: Zusammenfassung Der mittlere δ13C-Wert im CO2 der Atemluft von Europäern (Basiswert −26‰) zeigt eine Langzeitschwankung über mehrere Monate von ±1,0‰; der Verzehr von Produkten aus C4-Pflanzen (z. B. Mais) hat allerdings erheblich höhere Änderungen zur Folge. Im Nüchternzustand und in Ruhe wird während 6 h eine Stabilität des Basiswertes von ±0,3‰ erreicht; nach längeren Nüchternphasen kann aber der Abbau körpereigener Substanzen zu Verschiebungen führen. Durch Umstellung der Energieversorgung auf Maisprodukte ist es möglich, den Basiswert innerhalb eines Tages auf −18‰ zu heben; dann läßt sich auch der Abbau von Substanzen aus C3-Pflanzen verfolgen. Der Verlauf und die Rate des Abbaues von markierten Fetten sind stark von der Art der Applikation abhängig, und die Messung des Gesamtumsatzes wird durch den Untergrund stark beeinträchtigt. Der Zeitpunkt des maximalen Abbaues von uniform markiertem Fett (Sojaöl) unterschied sich von dem eines in der Carboxylgruppe markierten Trilinoleats. Die Resultate sind Grundlage zur Einstellung bzw. Korrektur von Basiswerten bei13C-Atemtests, besonders bei Patienten mit parenteraler Ernährung.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02026207
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  • 10
    Electronic Resource
    Electronic Resource
    On the ultrastructure of the gastric “borderline lesion” (1983)
    Springer
    Journal of cancer research and clinical oncology 105 (1983), S. 285-291 
    Details
    ISSN: 1432-1335
    Keywords: Borderline lesion ; Severe dysplasia ; Gastric precancerosis ; Electron microscopy ; Morphometric analysis ; Bleb formation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The “borderline lesion” of the stomach (severe dysplasia of the protruded type) is nowadays considered to be a true precancerous lesion. Histologically, this lesion is characterized by a proliferation in the area of the glandular neck, combined with severe cellular atypia. Investigation by means of transmission electron microscopy reveals the structure of these cells to be very similar to the structure of cells of an intestinal-cell-type carcinoma of the stomach. In addition to signs for a loss of differentiation of the cells, such as the absence of rough-surfaced endoplasmatic reticulum, mucin granules, and of the polarity of the cells, remarkably frequently luminal bulges and “blebs” developed to various extents can be detected. Morphometric analysis is delineating the tendency of structural features of the borderline lesion to develop toward the gastric cancer cell. These irregularities might be expressions of the beginning of expansive growth and signs pointing to differentiation into malignant neoplasia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00395760
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