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  • 1980-1984  (13)
  • 1915-1919
  • 1900-1904
  • 1984  (13)
  • 1
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Sociology 10 (1984), S. 461-482 
    ISSN: 0360-0572
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Sociology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 11 (1984), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of immunology 20 (1984), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Human monocyles release cytostatic protein factors (CF) upon activation with lymphokines und lipopolysacchairide. CF has been purified from monocyte supernatants by ion-exchange chromatography. chromatofocusing and gel filtration, and this resulted in a 10,000-fold reduction in the amount of protein in the purified CF preparation compared to the amount in the monocyte supernatant. About 5% of the eytostatic activity was recovered after purification. CF constitutes a population of proteins heterogeneous with respect to ionic charge and differing in their isoelectric points, since CF eluted as a broad peak both upon ion-exchange chromatography and chromatofocusing. The isoelectric points of the CF proteins were determined by chromatofocusing to be between 6.0 and 5.0. The molecular weight of CF as determined by gel filtration was in the range of 45,000 to 35,000 daltons. Only one monocyte-secreted protein with a molecular weight of 40,000 was detected upon sodium dodecyl sulphate-polyacrylamide gel electrophoresis of proteins in the purified CF preparations obtained after the final gel filtration step, und this protein may consequently be CF. If the 40,000-dalton protein is CF. one may estimate that about 106 monocytes produced roughly 0.1 μg CF upon activation and that significant cytostasis may be detected with less than nanogram quantities of CF.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 276 (1984), S. 52-56 
    ISSN: 1432-069X
    Keywords: Fluorometry ; DNA ; 4′-6-Diamidino-2-phenylindole ; Fibroblasts ; Epidermis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 4′-6-diamidino-phenylindole (DAPI) which is used for the detection of mycoplasmic infections of cell cultures or cytofluorometric investigations proved to be a sensitive agent for the fluorometric assay of alkali extracted DNA in cultured cells and human epidermis. Various experiments to optimize assay conditions led to the following procedure: 1 part of freeze dried tissue (1 mg/ml) and 1 part of 0.2 mol/l NaOH (w/v) were heated at 95° for 40 min. After cooling for 1 h to room temperature, 0.1 ml alkaline extract was mixed with 2.9 ml DAPI-solution (0.2 μg/ml in McIlvaine buffer containing 1 mmol/l MgCl2). After 10 min in the dark the emitted fluorescence was estimated at 453 nm with an excitation at 360 nm. This assay procedure allowed a detection limit of 25 ng DNA.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1041
    Keywords: benzodiazepine antagonist ; visual function ; intrinsic effect ; Ro 15-1788 ; healthy volunteers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Ro 15-1788 is a specific benzodiazepine antagonist, which has also been shown to have some agonist properties. Since benzodiazepine receptors are involved in the physiological mechanisms of vision, a possible intrinsic effect of Ro 15-1788 was sought in 6 healthy volunteers by study of psychophysical flicker thresholds, including critical fusion frequency and low frequency modulation threshold, and pattern reversal visual evoked response, using double blind cross-over methodology. In each session 2 tablets of Ro 15-1788 30 mg were administered. Using a two factorial univariate analysis of variancé, no change was detected in any of the parameters studied.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of comparative physiology 154 (1984), S. 659-668 
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effects of gonadal steroids upon the discharge frequencies of the weakly electric fishApteronotus rostratus were examined. Androgens elicited frequency decreases, while estrogens had no effect. The androgen-induced decreases occurred with very short latencies and lasted only for several hours. The medullary nucleus that controls the discharge frequencies of these animals was subsequently isolated in an in vitro preparation. The effects of steroids were tested on the isolated pacemaker, and were found to be similar to those seen in intact animals. Thus, steroid effects upon discharge frequencies appear to be a consequence of direct effects upon the pacemaker. The short time course of the response suggests non-genomic effects of steroids upon neuronal activity in the pacemaker.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1351
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Previous studies indicated that gonadal steroids can induce changes in both motor and sensory aspects of the electrosensory system of weakly electric fish: androgens decrease the electric organ discharge frequencies and electroreceptor best frequencies of the South American gymnotoidSternopygus. The relationship between these two effects, however, was not known. In the present study, electric organ discharges (EODs) ofSternopygus dariensis were eliminated by means of spinal cord transections. This was done in order to allow an independent assessment of the influences of gonadal steroids upon electroreceptor tuning and those structures in the CNS responsible for establishing the discharge frequency. Transection alone affected neither the rhythmic discharges of the pacemaker nucleus that normally controls the discharge frequency, nor the best frequencies of electroreceptors. Similarly, administration of the androgen 5α-dihydrotestosterone (DHT) to transected animals also had no significant effect upon electroreceptor tuning. DHT did, however, cause significant decreases in the discharge rates of the pacemaker nucleus. Thus, the effects of gonadal steroids upon discharge frequencies in intact animals are a direct consequence of CNS influences, while effects upon electroreceptor tuning likely arise as a secondary consequence of the changed discharges of hormone-treated animals.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Sozial- und Präventivmedizin 29 (1984), S. 192-193 
    ISSN: 1420-911X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The visual examination of drivers is usually limited to the measurement of photopic visual acuity. This study shows that it would be more appropriate, particularly for night driving, to measure the recovery time after glare, as well as the acuity-luminance relationship in mesopic conditions.
    Abstract: Zusammenfassung Im allgemeinen wird bei PKW-Fahrern nur die photopische Sehschärfe geprüft. Es wäre jedoch besser, im besonderem für Nachtfahrt, die Umstellungszeit nach Blendung und die Beziehung Sehschärfe-Luminanz in mesopischen Lichtbedingungen zu messen.
    Notes: Resume L'examen visuel des conducteurs se borne, généralement, à la détermination de l'acuité visuelle photopique. Cette étude montre, en particulier pour la conduite nocturne, qu'il serait plus approprié de déterminer le temps de récupération après éblouissement et la relation acuité-luminance en condition mésopique.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Transverse particle momenta have been measured ine + e − annihilation into hadrons at c.m. energies between 9.4 and 31.6 GeV. The data are fully corrected for detector effects and radiation in the initial state. A comparison is made with recent QCD calculations.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The processγγπ+π− has been measured with complete particle identification. Cross-sections are presented from near threshold up to the region of thef(1270). In the mass range 0.5–0.7 GeV, crosssections are lower than the Born term predictions and show no evidence for an ε(600). The two-photon width of thef(1270) is found to be in agreement with previous results.
    Type of Medium: Electronic Resource
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