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  • 1985-1989  (6)
  • 1960-1964
  • 1986  (6)
Material
Years
  • 1985-1989  (6)
  • 1960-1964
Year
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 13 (1986), S. 0 
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Normal epidermis of various sites of human body was examined by N-(7-dimethyl-amino-4-methyl-3-coumarinyl)maleimidc (DACM) method for SH groups and SS linkages. The horny cells in the palm and sole showed a gradual occurrence of a SH membranous pattern, while those in other sites revealed an abrupt formation of the SH membranous pattern just above the granular layer. In the palm and sole epidermis the number of layers which exhibit membranous pattern of SH-positivity was thicker than that in the other epidermis; the low- through mid-layers of horny cells in the former sites seemed to contain not only SS-positive but also SH-positive substance at cell peripheries. The DACM staining for SS linkages showed the presence of a granular fluorescence in the cytoplasm of the granular cells of the epidermis in the human palm and sole, but not in other sites. The granular cells in human lip displayed a granular fluorescence in the cytoplasm by cither SH or SS DACM staining. All the SH- or SS-positive granular fluorescence was related to keratohyaline granules. These findings indicate that there may be some variations of the distribution pattern of the epidermal cellular proteins with SH and/or SS and a difference in chemical composition of keratohyaline granules between different anatomical sites of human body.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Mineralogy and petrology 35 (1986), S. 193-216 
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Drei Kimberlitvorkommen wurden im Rahmen von Bohrungen aeromagnetischer Anomalien im Nyanzian-Gebiet im Westen Kenias entdeckt. Die drei Vorkommen (Y1B1, Y1B3 und YA17) bestehen aus teilweise geschichteter Diatremfazies und untergeordnetem Kraterfazies-Material. In einigen Horizonten treten Anhäufungen ultramafischer Xenolithe auf, die wiederholte Sortierungsvorgänge im Spätstadium der Diatrementwicklung andeuten. Die Kimberlitvorkommen im Westen Kenias sind frei von Chrom-Granat, Ilmenit und Spinell als Mantelxenokristalle. Olivin, der aus Kimberlit-Magma kristallisierte, ist frei von CaO und zeigt einen MgO/(MgO+FeO)-Bereich. Phlogopit (I, II und III) zeigt drei verschiedene Zusammensetzungen. Typ I weist niedrige TiO2-und variable Cr2O3, FeO und Al2O3-Gehalte auf; Typ II ist hoch in TiO2 und FeO, relativ hoch in Al2O3 und niedrig in Cr2O3; der dritte Typ ist reich an TiO2, Cr2O3 und Al2O3, bei relativ hohen FeO-Gehalten. Zonierter Phlogopit weist im Kern die Zusammensetzung der Typen I und II, und im Randbereich die der dritten Varietät auf. Phlogopite der Zusammensetzung I werden im Mantel zugeordnet und Typ II der unteren Kruste, während Typ III aus dem Kimberlitmagma kristallisierte. Die Zusammensetzung der Amphibole entspricht Richterit, Edenit, edenitischer Hornbende und Magnesio-Katophorit, die alle auf Interaktionen zwischen ultramafischen Xenolithen und einer volatilen Phase des Kimberlitmagmas zurückgefuhrt werden. Die chemische Zusammensetzung der Y1B1-Kimberlite zeigt niedrige K2O-Gehalte und K2O/Na2O-Verhältnisse. YA17 ist relativ arm an K2O und reich an Na2O; dies ist auf hohe Gehalte an Natrolit, Thomsonit, Cancrinit und Sodalit zurückzuführen. δ13C und δ18O der Karbonate im Y1B1-Kimberlit sind schwerer als gewöhnlich; dies weist auf Interaktionen mit meteorischen Wässern während der Diatremphase hin. Das Vorkommen Y1B3 ist ein stark verwittertes Equivalent des Kimberlites YA17. Die ultramafischen Xenolithe bestehen größtenteils aus granatfreiem Harzburgit und Dunit, und untergeordnet Hornblendit. Harzburgite sind an Al2O3, CaO und Na2O angereichert. Es wird vermutet, daß die Platznahme der Kimberlitvorkommen im Westen Kenias eine Folge der Entstehung des Kavirondo-Rifts ist.
    Notes: Summary Three kimberlites were found at drilling points showing aeromagnetic anornalies in Nyanzian terrane in western Kenya. Three kimberlites, Y1B1, Y1B3 and YA17, are composed of diatreme facies materials with partly laminated structure and thin crater facies deposits. A few horizons with concentrated ultramafic xenoliths are found. These occurrences suggest repeated stirring in the diatremes by weak blows at the late stage of diatreme development. Western Kenya kimberlites are free of mantle-derived chromian garnet, ilmenite and spinel. Olivines crystallizing from kimberlite magma may contain small amounts of CaO, showing wide spread in MgO/(MgO+FeO) ratios. Three compositional types (I, II and III) of phlogopites are identified. Type I phlogopites are low in TiO2 with variable contents of Cr2O3, FeO and Al2O3, type II high in TiO2 and FeO with relatively high Al2O3 and low Cr2O3, and type III high in TiO2, Cr2O3 and Al2O3 with relatively high FeO. The core part of zoned phlogopites is assigned to either type I or type II and associated with the rim of type III. Type I phlogopites are derived from mantle and type II from the lowest crust or upper mantle, whereas type III crystallized in the kimberlite magma just before diatreme emplacement. Amphiboles comprise richterite, edenite, edenitic hornblende and magnesiokatophorite, all of which are discrete ultramafic rocks or later stage-interaction products between ultramafic xenoliths and kimberlite fluid. Bulk chemistry of Y1B1 kimberlites shows low K2O content and low K2O/Na2O ratio. YA17 kimberlite shows fairly low K2O and high Na2O contents owing to the occurrence of natrolite and/or thomsonite, cancrinite and rare sodalite. The values of δ13C and δ18O of carbonate in Y1B1 kimberlite are heavier than those of common kimberlites, suggesting meteoric-hydrothermal water interaction during the diatreme emplacement. The kimberlite, Y1B3, which is intensely weathered, is mineralogically similar to YA17 kimberlite. Ultramafic xenoliths in western Kenya kimberlites consist mainly of garnet-free harzburgite and dunite, with small amount of hornblendite. The harzburgites are fairly rich in Al2O3, CaO and Na2O. The emplacement of western Kenya kimberlite diatremes is considered to have been structurally controlled by the development of the Kavirondo Rift.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Origins of life and evolution of the biospheres 16 (1986), S. 510-511 
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 279 (1986), S. 112-119 
    ISSN: 1432-069X
    Keywords: Innermost cell layer ; Outer root sheath ; Anagen hair follicle ; Keratinization ; Light and electron microscopes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To investigate cell differentiation in the outer root sheath (ORS) of the human anagen hair follicle, scalp skin specimens from individuals with normal hair were examined using light and electron microscopes. In the bulbar portion, the ORS was composed of two cell layers. The cells in the outer layer gradually increased in number upwards and finally underwent so-called trichilemmal keratinization, which proceeded toward the hair canal. On the other hand, the inner cells in the bulb formed a single cell layer along the outside of Henle's layer during cell differentiation; this unique layer was referred to as the innermost cell (IMC) layer of the ORS. With the use of hematoxylin and eosin stain, at the suprabulbar portion, where Henle's cells were keratinizing, an eosinophilic substance was deposited in the inner (Henle's) side of the IMC cytoplasm. The IMCs gradually became entirely eosinophilic and often produced keratohyaline granules. Ultrastructurally, the IMCs of the ORS showed an oblong shape forming a regularly arranged single-cell layer along the keratinizing Henle's layer and accumulated tonofilaments in the cytoplasm. They produced a few small electron-dense keratohyaline granules and were keratinized at the level at which Henle's layer still preserved its cell structure. From these findings, it is suggested that there are two types of keratinization of the ORS: trichilemmal keratinization and IMC keratinization.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sodium dichloroacetate (DCA) was administered orally at a dose of 50 mg per kg body weight twice or three times per day to a newborn infant with lactic acidosis of unknown cause (patient 1) and to a 15-year-old boy with mitochondrial encephalomyopathy associated with lactic acidosis (patient 2). In patient 1, during treatment with DCA, DCA accumulated in the blood judging from the findings that the urinary excretion of DCA increased cumulatively and the blood lactate level rapidly decreased to the normal range. In patient 2, the blood DCA level gradually increased during treatment to a concentration of 250 µgml−1 and the blood lactate level decreased and was maintained within the normal range. DCA was detected in the brain (25 µg g tissue−1) and the liver, kidney and muscle (33.8, 33.8 and 26.3 µg g tissue−1, respectively) obtained at autopsy of patient 1, and in the cerebrospinal fluid of patient 2 at a concentration of 125 µg ml−1 when the blood concentration was 250 µg ml−1. The lactate levels in the cerebrospinal fluid decreased from 7 and 4mmoll−1 to 2.4 and 2.6 mmoll−1 in patients 1 and 2, respectively. Thus DCA may be useful in clinical treatment of chronic congenital lactic acidosis because it seems to cross the blood-brain barrier. However, it must be given at non-toxic doses, determined by monitoring the concentrations of lactate and DCA in the blood, because orally administered DCA tends to accumulate in tissues.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Origins of life and evolution of the biospheres 16 (1986), S. 494-495 
    ISSN: 1573-0875
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Type of Medium: Electronic Resource
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