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  • 1985-1989  (3)
  • 1925-1929
  • 1880-1889
  • 1850-1859
  • 1986  (3)
  • Engineering  (2)
  • Genetics
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular genetics and genomics 205 (1986), S. 507-514 
    ISSN: 1617-4623
    Keywords: Pyridine nucleotide cycle ; NAD metabolism ; Salmonella typhimurium ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A series of Mud1 and Tn10 insertions were identified in the pncA chromosome region of Salmonella typhimurium which is responsible for the production of nicotinamide deamidase. Both pncA (resulting in no nicotinamide deamidase activity) and pncX (resulting in lowered nicotinamide deamidase activity) insertions were constructed. In addition, mutants which could utilize nicotinamide as a sole source of nitrogen were isolated. These mutants, designated pncH, hyperproduce nicotinamide deamidase. Genetic studies utilizing pncX-lacZ and pncA-lacZ operon fusions indicate that pncX::Tn10 insertions reduce transcription of pncA-lac while pncH mutations increase the expression of both pncA-lacZ and pncX-lacZ. The gene order was determined as purB-pncA-pncX-gdh with transcription of both pncA and pncX occurring in the counterclockwise direction. Merodiploid studies suggest a model whereby pncX and pncA form an operon with the major promoter occurring upstream from pncX. A second, weaker promoter for pncA must be situated between pncX and pncA. The pncH mutations appear to occur in the pncX promoter (pncXp) increasing promoter activity.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    International Journal for Numerical Methods in Engineering 23 (1986), S. 1915-1937 
    ISSN: 0029-5981
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: Finite element and boundary element methods are described for predicting high-frequency electromagnetic heating of tissue as a cancer therapy. For the class of clinical problems of interest, the patient is electrically inhomogeneous and best discretized by finite elements, but the unbounded nature of practical source configurations calls for a boundary element approach. A hybrid is introduced which couples the two methods and is superior in algebraic requirements to either method alone. The formulation is three-dimensional and allows exact satisfaction of the electromagnetic jump conditions at interfaces separating distinct tissue types. Test cases show its validity for transverse magnetic and electric situations with known solutions. Examples of clinical applications are shown.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 10 (1986), S. 115-123 
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: Precast concrete pavement units are used in areas with low subgrade CBR values and high static and dynamic loadings. Unlike flexible pavements and rigid pavements, there are no design charts from which pavement engineers can design precast concrete pavements. The author has investigated analytically the relative importance of the factors affecting the ultimate stress and subgrade bearing pressures in precast concrete pavements. Presenting the results in graphical form, the design charts are used toillustrate the new design method.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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