ISSN:
1432-2099
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Physics
Notes:
Summary Within the Theory of Dual Radiation Action, the heuristically useful function,γ(ϰ), that two energy depositions, a distanceϰ apart, will result in observable damage can be written in terms of two more fundamental quantities: One,s(ϰ), describes the structure of the sensitive matrix of the cell. The other,g(ϰ), describes the probability that two elementary injuries, a distanceϰ apart, will combine to produce observable damage. A priori, the known enhancement exhibited byy(ϰ) at nanometer separations could be due to an enhancement ofs(ϰ),g(ϰ) or both. For the endpoint of chromatid exchanges in Chinese hamster cells,γ(ϰ) has been evaluated from experimental data ands(ϰ) from a model system. From theseg(ϰ) has been estimated and is roughly constant below ∼ 1 µm, decreasing rapidly at larger separations. Thus the enhanced short-range effect appears to be a function more of the spatial characteristics of the target rather than the probability of damage interaction.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01210836
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