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  • 1985-1989  (4)
  • 1988  (4)
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  • 1985-1989  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    Prophylaxis of aspirin-induced gastric mucosal bleeding with ranitidine (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Alimentary pharmacology & therapeutics 2 (1988), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The ability of ranitidine to protect the human gastric mucosa against aspirin-induced damage was investigated by timed measurements of blood loss collected by gastric washing. Ranitidine (150 mg) 1 h or 5 h before 900 mg aspirin (5 doses of each) over 48 h reduced subsequent mean bleeding from 7.7 μi/10 min to 2.6 μl/10 min or 3.4 μl/10 min, respectively. Both regimens were antisecretory at the time of aspirin administration, as judged by a rise in the pH of the aspirated washings. The prolonged protection against aspirin-induced bleeding achieved with twice daily dosing with ranitidine has dinical potential in the management of patients taking anti-inflammatory drugs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.1988.tb00694.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Gillon, Raanan: Philosophical Medical Ethics : London, John Wiley and Sons, 1986 (1988)
    Cambridge : Cambridge University Press
    Philosophy 63 (1988), S. 552-554 
    Details
    ISSN: 0031-8191
    Source: Cambridge Journals Digital Archives
    Topics: Philosophy
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0031819100043928
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Applications of a new low temperature differential scanning calorimeter (1988)
    Springer
    Journal of thermal analysis and calorimetry 33 (1988), S. 379-384 
    Details
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Ein neues Tieftemperatur-Differential-Scanning-Kalorimeter für den Bereich von −120 °C bis+700 °C wird beschrieben. Das Gerät enthält eine Wärmefluss-DSC-Sensorplatte aus Chromel in einer Heizkammer aus einer Kobaltlegierung, was Arbeiten in oxidierender Atmosphäre bis über 600 °C ermöglicht. Ein IBM-kompatibles Computersystem bietet alle Möglichkeiten der Datenverarbeitung und Programmregelung. Die Leistungsfähigkeit des Geräts wird an Hand von Experimenten mit Indium und Polyvinylchlorid demonstriert.
    Abstract: РЕЗЮМЕ Описан новый низкоте мпературный дифференциальный ск анирующий калоримег р, работающий в интерва ле температур от —150° д о 700°. Характерной деталью ДСК аппаратуры является чувствител ьная к тепловому пото ку пластинка из хромеля, находящая ся в кобальтовом сплаве камеры нагрев а и дающая возможност ь проводить измерения в окислите льной атмосфере выше 600°. Полная обработ ка данных и программи рованный контроль осуществля ется с помощью IBM компьютерн ой системы. Действие а ппаратуры показано на эксперим ентальных примерах с индием и по ливинилхлоридом.
    Notes: Abstract A new low temperature differential scanning calorimeter is described which operates over the temperature range −150 °C to 700 °C. The equipment features a chromel heat flux DSC sensor plate located in a cobalt alloy heating chamber, enabling work to be carried out in oxidizing atmospheres to above 600 °C. Full data processing and programme control facilities are provided by an IBM compatible computer system. The performance of the instrument is illustrated by experiments on indium and poly (vinyl chloride).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01914628
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The toxicity of alkyllead compounds to Scrobicularia plana (Da Costa) (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Applied Organometallic Chemistry 2 (1988), S. 143-149 
    Details
    ISSN: 0268-2605
    Keywords: Scrobicularia ; alkyllead compounds ; toxicity ; inhalent siphon ; bivalves ; Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Conventional (whole animal) toxicity tests were made with Scrobicularia plana (Da Costa), an infaunal estuarine bivalve, and compared with the responses recorded from siphonal preparations. Exposure of Scrobicularia to low concentrations of triethyllead chloride and trimethyllead chloride, for 35 and 60 days respectively, produced typical response curves. However, mortality had not become asymptotic with time at lower concentrations, suggesting further mortality with increased exposure time. An approximate incipient lethal concentration was predicted.A siphonal preparation technique with isolated and in-situ inhalent siphons of Scrobicularia was used to estimate the lowest effect concentrations of alkyllead compounds. Response to alkyllead was indicated by contraction of the siphon, recorded via an isotonic transducer. Trialkyllead compounds were more toxic than the respective dialkylleads and inorganic lead. Toxicity of trialklleads and inorganic lead. Toxicity of trialkylleads increased with alkyl chain length. Pure tetraethyllead did not cause any siphonal contraction even when applied directly to the preparation. It was concluded that tetraethyllead has a low toxicity or is non-toxic in pure form.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aoc.590020208
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    Paper (German National Licenses)
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