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  • 1985-1989  (3)
  • 1940-1944
  • 1989  (3)
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Material
Years
  • 1985-1989  (3)
  • 1940-1944
Year
  • 1
    Electronic Resource
    Electronic Resource
    Effects of cyclopiazonic acid and aflatoxin singly and in combination on selected clinical, pathological and immunological responses of guinea pigs (1989)
    Springer
    Mycopathologia 105 (1989), S. 135-142 
    Details
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Cyclopiazonic acid (CPA) and aflatoxin are known sometimes to coexist in nature but little is known of possible biological interaction in mammals that consume mixtures of these two mycotoxins. Guinea pigs were dosed orally with CPA (2.2 mg/kg) or aflatoxin (0.045 mg B1/kg) singly or in combination. Effects of toxin consumption were determined on clinical health, body weight gain, pathological change, and several immunologically related parameters including delayed cutaneous hypersensitivity, antibody response, complement hemolytic titer, intracutaneous mitogen (PHA) and in vitro lymphocyte blastogenesis. In contrast to an earlier study by others, significant synergy between these two toxins was demonstrated in reduced rate of body weight gain, lethality and histologic changes (vacuolization) in hepatocytes. Reductions in complement titer, intradermal PHA, delayed cutaneous hypersensitivity response and in vitro lymphocyte blastogenesis were related to aflatoxin activity. No effects on antibody formation to Brucella abortus were observed with either toxin or the combination of toxins. Cyclopiazonic acid appeared to restore the suppressive effects of aflatoxin in delayed cutaneous hypersensitivity response and in vitro lymphocyte blastogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00437245
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Continuous effluent consents: Modelling and compliance testing (1989)
    Springer
    Environmental monitoring and assessment 13 (1989), S. 149-164 
    Details
    ISSN: 1573-2959
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract The control of continuous polluting discharges in the U.K. was placed in a framework of statistically based legislation nearly 10 years ago. Both discharge standards and desired river quality class objectives are assessed within a probabilistic system of pollution control whereby a minimum level of 95 percent compliance with standards has to be achieved. The use of such a statistical framework permits occasional infringements of what would otherwise be fixed standards. This enables the Water Industry to manage river quality without undue risk of prosecution or unnecessary capital expenditure on effluent treatment. The change to a statistically based system has been a slow process carried out in stages: from the introduction of a river quality classification; setting long term river quality objectives; then setting discharge consents to achieve these objectives; and finally monitoring compliance with the consents and objectives. Each of these stages has required the development of the necessary statistical tools for river quality planning and management. Due to the decentralised nature of the currently catchment-based Water Authorities, several different statistical approaches have been adopted. However, if, as is planned for the near future, river quality management is carried out by a national regulatory body, then some rationalisation of current methodologies will have to be undertaken. This paper introduces and examines current U.K. approaches to river quality management and pollution control. Particular emphasis is placed on the statistical modelling techniques used for consent setting and compliance testing. Some of the commonly used techniques are compared and evaluated. A description is presented of work that is underway to develop a framework for the establishment and assessment of intermittent pollution control criteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00394227
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Book reviews (1989)
    Springer
    Chromatographia 28 (1989), S. 423-425 
    Details
    ISSN: 1612-1112
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02261029
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    Paper (German National Licenses)
    Fulltext
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