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  • 1985-1989  (1)
  • 1989  (1)
  • Fluid Replacement  (1)
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  • 1985-1989  (1)
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  • 1989  (1)
  • 1
    ISSN: 1432-1238
    Keywords: Burns ; Inhalation injury ; Resuscitation ; Fluid Replacement
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We have studied 9 patients with burns (20%–75%) who had inhalation injuries and compared their actual fluid requirements with their requirements calculated from the Muir and Barclay formula. All patients were resuscitated with plasma protein fraction at a rate sufficient to keep their physiological variables within the following range: heart rate 〈120/min, central venous pressure 8–12 cm H2O, urine output 〉30–50 ml/h, systolic blood pressure 〉90 mm Hg and diastolic blood pressure 〉60 mm Hg. The amount of plasma protein fraction needed was 4.38±1.26 ml/kg/% burn in the first 24 h and 2.15±0.97 ml/kg/% burn in the second 24 h. This is an increase of 75% and 110% respectively above values predicted from the formula. We suggest that the observed difference is due to a combination of the presence of an inhalation injury which increases fluid requirements by approximately 30% in the first 24 h and the use of plasma protein fraction rather than the dried plasma used in the original Muir and Barclay formula.
    Type of Medium: Electronic Resource
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