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  • 1990-1994  (2)
  • 1991  (2)
  • Brainstem  (1)
  • Carotid body  (1)
Material
Years
  • 1990-1994  (2)
Year
  • 1991  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 86 (1991), S. 324-332 
    ISSN: 1432-1106
    Keywords: Vision ; Optokinetic nystagmus ; Eye movements ; Plaids ; Brainstem ; Motion perception ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have recorded the direction of optokinetic nystagmus (OKN) elicited by moving plaid patterns in order to dissociate the pathways that mediate horizontal OKN. The plaids used comprised two drifting sinusoidal gratings arranged such that their individual directions of drift were very different from the direction of coherent motion of the overall pattern. The direction of OKN with binocular viewing was close to the mean of the component directions, suggesting a dominant influence of cortical visual neurons that respond to oriented one-dimensional components of the image. But the direction of OKN was consistently shifted slightly towards the direction of motion of the overall pattern, suggesting a secondary influence responsive to pattern direction. OKN recordings obtained during monocular viewing suggest that this secondary influence reflects the direct retinal pathway to the brainstem structures mediating OKN.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 40 (1991), S. 175-180 
    ISSN: 1432-1041
    Keywords: Adenosine ; Anoxia ; Carotid body ; Respiration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Intravenous infusion of the nucleoside adenosine stimulates respiration, probably at least partly by an action in the carotid bodies, and also potentiates the ventilatory response to hypoxia, suggesting that it might be involved in the control of breathing. Whether the effects of adenosine occur at concentrations likely to be achieved in vivo is unknown and was investigated in 7 patients with arterial catheters inserted for diagnostic purposes. During intravenous infusion of adenosine (Maximum dose per min: mean 130 μg kg−1) mean minute ventilation increased from 5.5 to 10.9 l min−1 while mean plasma adenosine concentration in the aortic arch increased from 0.07 to 1.2 μM. In 3 patients ventilation first increased without a detectable increase in aortic adenosine concentration, suggesting a possible intra-pulmonary effect of adenosine, although increased concentrations were apparent at higher doses. Micromolar concentrations of adenosine are probably achieved in vivo in tissues during hypoxia. The present results show that at such concentrations adenosine stimulates respiration and are consistent with the suggestion that adenosine release may mediate or modulate the ventilatory response to hypoxia. A possible intra-pulmonary effect of adenosine merits further study.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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