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Digitale Medien

Association of HLA antigens with differential responsiveness toMycobacterium w vaccine in multibacillary leprosy patients (1992)

Rani, Rajni ; Zaheer, S. A. ; Suresh, N. R. ; [weitere]

Springer

Journal of clinical immunology 12 (1992), S. 50-55

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ISSN: 1573-2592

Schlagwort(e): HLA ; lepromin conversion ; histopathological upgrading ; lepromatous leprosy

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Leprosy patients undergoing phase II trials in two hospitals of New Delhi, India, were HLA typed to see the association of HLA with differential responsiveness toMycobacterium w vaccine. The vaccine comprises an atypical, nonpathogenic mycobacterium,Mycobacterium w, which has cross-reactive antigens withM. leprae. Multibacillary patients who are lepromin negative are vaccinated at an interval of 3 months. Considerable improvement is evident in the patients in terms of a decline in bacterial indices and histopathological and immunological upgrading. But all the patients do not respond to the vaccine in the same manner; some are slow responders, while others are good responders. HLA-A28 and DQw3 (DQw8+9) were found to be associated with slow responsiveness, while DQw1 and DQw7 were found to be associated with a more rapid responsiveness to theM. w vaccine. However, these associations were not significant afterP correction for the number of antigens tested for each locus except for HLA-DQw3 (DQw8 and DQw9) and DQw7. DQw7, a new defined split of HLA-DQw3, seems to be associated with the responsiveness toM. w vaccine.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00918273

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Digitale Medien

Microstructural changes of polycrystalline nickel during high-temperature deformation at ambient and high pressures (1992)

Groza, J. ; Meagher, S. ; Borch, R. S. ; [weitere]

Springer

Journal of materials science 27 (1992), S. 3963-3968

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ISSN: 1573-4803

Quelle: Springer Online Journal Archives 1860-2000

Thema: Maschinenbau

Notizen: Abstract The microstructures of polycrystalline nickel, deformed in compression at temperatures of 1000–1500 K at high pressure (1500 MPa) and at ambient (0.1 MPa) pressure, were compared. Dynamic recrystallization and strain-induced grain growth were observed to occur during creep tests at both pressure levels. Our experimental results at ambient pressure are in good agreement with Sandstrom and Lagneborg's theory on dynamic recrystallization. However, high-pressure application considerably retarded recrystallization and grain-growth kinetics. This behaviour was attributed to an increase in the activation energy for grainboundary migration at high pressure.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00545481

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Digitale Medien

Effect of cooling rate in overageing and other thermomechanical process parameters on grain refinement in an AA7475 aluminium alloy (1992)

Yang, H. S. ; Mukherjee, A. K. ; Roberts, W. T.

Springer

Journal of materials science 27 (1992), S. 2515-2524

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ISSN: 1573-4803

Quelle: Springer Online Journal Archives 1860-2000

Thema: Maschinenbau

Notizen: Abstract Fine-grained AA7475 aluminium alloy sheets were produced in this study by a thermomechanical treatment involving solution anneal, overageing, rolling and recrystallization steps. It has been found that the cooling rate after the intermediate overageing treatment should be fast to obtain the finest grain size. The fast cooling rate ensured the presence of relatively large particles of MgZn2 and some supersaturation prior to cold rolling. Generally, the final grain structure was heterogeneous, with bands of fine grains lying parallel to the rolling direction. In material rapidly cooled after overageing, bands of fine grains were also observed in the transverse direction and these bands were associated with shear bands formed during rolling. The fine-grained AA7475 alloy sheets with an average grain size of about 9 μm showed large tensile elongations of about 800% when deformed at 516 °C and with an initial strain rate of 5×10−4s−1.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01105064

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Digitale Medien

Thermal studies on brominated atactic polypropylene (1992)

Mukherjee, A. K. ; Mohan, Anita

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Polymer Science 44 (1992), S. 773-779

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ISSN: 0021-8995

Schlagwort(e): Chemistry ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie , Maschinenbau , Physik

Notizen: Thermal behavior of brominated atactic polypropylene (BAPP), obtained by thermal bromination of atactic polypropylene (APP), was evaluated by thermogravimetric analysis (TGA) and differential thermal analysis (DTA). It was found that the initial decomposition temperature (IDT) and char yield increase with the increase in bromine content while integral procedural decomposition temperature (IPDT) showed a decreasing trend. A comparative study of these value in inert and oxidative atmospheres has been made. DTA study shows that onset decomposition temperature (ODT) and glass transition temperature (Tg) increase with the increase in degree of bromination. The possible reasons for the occurring phenomena have been discussed.

Zusätzliches Material: 8 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/app.1992.070440504

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Digitale Medien

Adhesion studies of tyre cords with rubber. I. Synthesis and characterization of natural rubber graft copolymers (1992)

Egboh, S. H. O. ; Mukherjee, A. K.

New York, NY [u.a.] : Wiley-Blackwell

Journal of Applied Polymer Science 44 (1992), S. 233-238

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ISSN: 0021-8995

Schlagwort(e): Chemistry ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie , Maschinenbau , Physik

Notizen: Glycidyl methacrylate and N-vinyl pyrrolidone have been grafted onto natural rubber at 32°C using the simultaneous cobalt-60 irradiation technique. The natural rubber samples were swollen in the monomers for 24 h and thereafter subjected to gamma irradiation. The homopolymers formed in the graft copolymerization reactions and unreacted monomer were removed by solvent extraction using acetone and methanol for glycidyl methacrylate and N-vinyl pyrrolidone monomer, respectively. The influence of total dose and monomer concentration on the graft parameters was investigated. The dependence of the rate of grafting on the monomer concentration was found to be 0.93 and 0.80 for glycidyl methacrylate and N-vinyl pyrrolidone, respectively. DSC and TGA studies of the polymers were undertaken. Grafted copolymers based on glycidyl methacrylate were relatively less thermally stable compared with ungrafted natural rubber.

Zusätzliches Material: 6 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/app.1992.070440206

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