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Digitale Medien

Metalorganic deposition of high critical current thin films in the Bi-Sr-Ca-Cu-O system on {100} LaAlO3 substrates (1992)

Golden, S. J. ; Lange, F. F. ; Clarke, D. R. ; [weitere]

Woodbury, NY : American Institute of Physics (AIP)

Applied Physics Letters 61 (1992), S. 351-353

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Details

ISSN: 1077-3118

Quelle: AIP Digital Archive

Thema: Physik

Notizen: Superconducting thin films of the two Cu-layer phase in the Pb-doped Bi-Sr-Ca-Cu-O system have been fabricated on {100} LaAlO3 single crystals by the metalorganic deposition from ethyl hexanoate precursors. Thin films given heat treatments in air at 850–860 °C had resistive transitions with a Tc of 86–89 K. The zero-field transport critical current densities were in the range of 2–4×105 A/cm−2 at 77 K and 106 A cm−2 at 45 K in 200–300-nm-thick films. In contrast to c-axis oriented films grown on {100} MgO, x-ray pole figures show that the films grown on {100} LaAlO3 are epitaxial, a result confirmed by electron channeling patterns.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1063/1.107934

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Digitale Medien

The properties of cultured fetal human and rat brain tissue and its use as grafts for the relief of the Parkinsonian syndrome (1992)

Walters, A. M. ; Clarke, D. J. ; Bradford, H. F. ; [weitere]

Springer

Neurochemical research 17 (1992), S. 893-900

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Details

ISSN: 1573-6903

Schlagwort(e): Human fetal brain cultures ; neural grafting ; dopamine ; Parkinson's disease

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Primary cultures were derived from human fetal ventral mesencephalon and cerebral cortex at 7–11 weeks gestation, and from fetal rat mesencephalon and cortex at embryonic day 14–15. Immunohistochemical analysis of the mesencephalic cultures using antibodies to tyrosine hydroxylase (TH) showed between 0.1–0.5% of human cells to be TH positive and 0.1–1% of rat cells to be TH positive. HPLC analysis of extracts from the cultures showed that they had the ability to synthesise and store dopamine. Implantation of the cultured human and rat mesencephalic tissue into a 6-hydroxydopamine rat model of Parkinson's disease produced marked recovery from amphetamine induced rotational asymmetry in the recipient rats, but no such recovery was observed following implantation of cortical cultures. Histological examination demonstrated the presence of surviving human mesencephalic and cortical grafts at least 6 months after implantation. Implants of cultured fetal rat tissue were less obviously but still significantly effective in these experiments. These rat tissue grafts were detectable for periods of at least 6–8 weeks by histological staining.