ISSN:
1612-1112
Keywords:
Gas chromatography
;
Electron-capture detector
;
Polychlorinated biphenyls
;
Simplex optimization
;
Principal component factor analysis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A modified simplex technique has been applied to optimize the performance of an electron-capture detector under constant-current and constant-frequency pulse modes for the gas chromatographic analysis of polychlorinated biphenyls. Optimal performance was obtained by adjusting the four experimental parameters of pulse voltage, detector temperature, make-up gas flow rate, and reference current (or pulse frequency) using the signal-to-noise ratio of the eluting peak as the criterion. The results show that constant-current pulse mode has better sensitivity and dynamic range whereas the constant-frequency pulse mode has the lower detection limit. Subsequent principal component factor analysis indicated that similar performance is achievable using only three parameters.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02276194
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