ISSN:
1573-7284
Keywords:
Leptospirosis
;
Serological screening
;
Microcapsule agglutination
;
Passive agglutination
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Microcapsules, absorbed with two mixed antigens- each composed of 3 sonicated leptospira serovars — were developed in the past as a microcapsule agglutination test (MCA-LS) for the screening of clinical leptospirosis. Fof this study, fifty serum samples, taken at an earlier and at a later stage of illness from 25 Italian in-patients with clinical symptoms of leptospirosis, were tested with both the MCA-LS one-dilution test and the microscopic agglutination (MA) test, the confirmatory test for leptospirosis, with 18 leptospira strains circulating in Italy. Compared with MA, MCA-LS showed a sensitivity of 91.7%, and a specificity of 92.3%, including leptospiroses not substained by the diagnostic strains used in the MCA-LS kit.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00463096
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