ISSN:
1612-1112
Keywords:
α1-acid glycoprotein
;
Potassium channel activators
;
3,4-Dihydro-2,2′-dimethyl-2H-1-benzopyranenantiomers
;
Amide conformation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The amide conformers of two compounds and their enantiomers have been separated by liquid chromatography on an α1-acid glycoprotein column. The effects of organic modifier and pH on the separations obtained were investigated. The conformers of one of the compounds were separated micro-preparatively at low temperature on the same column using a D2O-based eluent; D2O had no deleterious effects on the chromatography obtained. Some preliminary competition experiments on one of the amides and a close analogue are presented.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02263846
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