Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1990-1994  (3)
  • 1993  (3)
  • serine dehydratase  (2)
  • Hereditary essential tremor  (1)
  • infrared spectroscopy
  • 1
    Electronic Resource
    Electronic Resource
    Assessing the impact of essential tremor on upper limb function (1993)
    Springer
    Journal of neurology 241 (1993), S. 54-61 
    Details
    ISSN: 1432-1459
    Keywords: Hereditary essential tremor ; Accelerometry ; Functional measures ; Suppressability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the impact of essential tremor on the performance of three manual tasks: drawing spirals, holding a cup full of water and a joystick-controlled tracking test. Tremor amplitude and frequency were measured by accelerometry during the tracking test, when holding the cup and whilst a standard posture was maintained. The inter-relationships between tremor amplitude, frequency and task impairment were then examined. The results showed that the amplitude and frequency of essential tremor (measured from the principal spectral peak) changed with different activities, with the mildest postural tremors changing most in frequency (by up to 4–5 Hz). The amplitude of tremor decreased in almost every case during the tasks, relative to posture, and this decrement was greatest for the most severe tremors. We also demonstrate that for practical purposes, such as routine clinical situations and therapeutic trials, the effect of essential tremor upon upper limb function can be usefully assessed by two simple complementary techniques: rating spirals and measuring the volume of water split from a cup. The impairments in carrying out these tasks and the tracking test were highly correlated with one another and also with the amplitude and frequency of postural tremor. The concept of tremor “suppressability” is introduced: the relative percentage decrease in the amplitude of a particular tremor during the performance of a specific task compared to that recorded whilst holding a standard posture.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00870673
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Four polymorphic markers on rat chromosome 12 form a single linkage group (1993)
    Springer
    Biochemical genetics 31 (1993), S. 441-448 
    Details
    ISSN: 1573-4927
    Keywords: linkage analysis ; serine dehydratase ; plasminogen activator inhibitor ; simple sequence repeats ; microsatellites ; rat chromosome 12
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Four PCR-typable polymorphic markers were mapped to rat chromosome 12 by linkage analysis of F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rat strains. The markers formed a single linkage group, covering 27.7 cM, with the following order and distance between markers: plasminogen activator inhibitor (Planh)—0.0 cM—phosphoenolpyruvate carboxykinase-related sequence 2 (Pepckr2)—15.4 cM—anonymous marker (D12N155)—12.3 cM—serine dehydratase (Sdh). All markers were identified and genotyped by PCR analysis of simple sequence repeats. The gene encoding Planh was previously assigned to rat chromosome 12, which allowed us to assign the entire linkage group to this chromosome. These markers were highly polymorphic in 13 additional inbred rat strains (BUF/N, BN/SsN, WKY/N, MNR/N, LER/N, WBB1/N, WBB2/N, MR/N, LOU/MN, SHR/N, ACI/N, SR/Jr, and SS/Jr). These markers should be useful tools for further genetic studies in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00553460
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Four polymorphic markers on rat chromosome 12 form a single linkage group (1993)
    Springer
    Biochemical genetics 31 (1993), S. 441-448 
    Details
    ISSN: 1573-4927
    Keywords: linkage analysis ; serine dehydratase ; plasminogen activator inhibitor ; simple sequence repeats ; microsatellites ; rat chromosome 12
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Four PCR-typable polymorphic markers were mapped to rat chromosome 12 by linkage analysis of F2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rat strains. The markers formed a single linkage group, covering 27.7 cM, with the following order and distance between markers: plasminogen activator inhibitor (Planh)—0.0 cM—phosphoenolpyruvate carboxykinase-related sequence 2 (Pepckr2)—15.4 cM—anonymous marker (D12N155)—12.3 cM—serine dehydratase (Sdh). All markers were identified and genotyped by PCR analysis of simple sequence repeats. The gene encoding Planh was previously assigned to rat chromosome 12, which allowed us to assign the entire linkage group to this chromosome. These markers were highly polymorphic in 13 additional inbred rat strains (BUF/N, BN/SsN, WKY/N, MNR/N, LER/N, WBB1/N, WBB2/N, MR/N, LOU/MN, SHR/N, ACI/N, SR/Jr, and SS/Jr). These markers should be useful tools for further genetic studies in rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02396228
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...