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  • 2005-2009
  • 1990-1994  (3)
  • 1925-1929
  • 1994  (3)
  • protein  (2)
  • Polymer and Materials Science  (1)
  • Lymantria dispar
  • Pseudotsuga menziesii
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  • 2005-2009
  • 1990-1994  (3)
  • 1925-1929
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  • 1
    Electronic Resource
    Electronic Resource
    The carnivore connection: dietary carbohydrate in the evolution of NIDDM (1994)
    Springer
    Diabetologia 37 (1994), S. 1280-1286 
    Details
    ISSN: 1432-0428
    Keywords: Diet ; diabetes ; carbohydrate ; protein ; evolution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We postulate a critical role for the quantity and quality of dietary carbohydrate in the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM). Our primate ancestors ate a high-carbohydrate diet and the brain and reproductive tissues evolved a specific requirement for glucose as a source of fuel. But the Ice Ages which dominated the last two million years of human evolution brought a low-carbohydrate, high-protein diet. Certain metabolic adaptations were therefore necessary to accommodate the low glucose intake. Studies in both humans and experimental animals indicate that the adaptive (phenotypic) response to low-carbohydrate intake is insulin resistance. This provides the clue that insulin resistance is the mechanism for coping with a shortage of dietary glucose. We propose that the low-carbohydrate carnivorous diet would have disadvantaged reproduction in insulin-sensitive individuals and positively selected for individuals with insulin resistance. Natural selection would therefore result in a high proportion of people with genetically-determined insulin resistance. Other factors, such as geographic isolation, have contributed to further increases in the prevalence of the genotype in some population groups. Europeans may have a low incidence of diabetes because they were among the first to adopt agriculture and their diet has been high in carbohydrate for 10,000 years. The selection pressure for insulin resistance (i.e., a low-carbohydrate diet) was therefore relaxed much sooner in Caucasians than in other populations. Hence the prevalence of genes producing insulin resistance should be lower in the European population and any other group exposed to high-carbohydrate intake for a sufficiently long period of time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399803
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The carnivore connection: dietary carbohydrate in the evolution of NIDDM (1994)
    Springer
    Diabetologia 37 (1994), S. 1280-1286 
    Details
    ISSN: 1432-0428
    Keywords: Key words Diet ; diabetes ; carbohydrate ; protein ; evolution.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We postulate a critical role for the quantity and quality of dietary carbohydrate in the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM). Our primate ancestors ate a high-carbohydrate diet and the brain and reproductive tissues evolved a specific requirement for glucose as a source of fuel. But the Ice Ages which dominated the last two million years of human evolution brought a low-carbohydrate, high-protein diet. Certain metabolic adaptations were therefore necessary to accommodate the low glucose intake. Studies in both humans and experimental animals indicate that the adaptive (phenotypic) response to low-carbohydrate intake is insulin resistance. This provides the clue that insulin resistance is the mechanism for coping with a shortage of dietary glucose. We propose that the low-carbohydrate carnivorous diet would have disadvantaged reproduction in insulin-sensitive individuals and positively selected for individuals with insulin resistance. Natural selection would therefore result in a high proportion of people with genetically-determined insulin resistance. Other factors, such as geographic isolation, have contributed to further increases in the prevalence of the genotype in some population groups. Europeans may have a low incidence of diabetes because they were among the first to adopt agriculture and their diet has been high in carbohydrate for 10,000 years. The selection pressure for insulin resistance (i. e., a low-carbohydrate diet) was therefore relaxed much sooner in Caucasians than in other populations. Hence the prevalence of genes producing insulin resistance should be lower in the European population and any other group exposed to high-carbohydrate intake for a sufficiently long period of time. [Diabetologia (1994) 37: 1280–1286]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399803
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Modelling studies of the controlled anionic copolymerization of butadiene and styreneDedicated to Professor Maurice Morton to commemorate the establishment of the Maurice Morton Institute of Polymer Science at the University of Akron. (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    Polymer International 33 (1994), S. 151-159 
    Details
    ISSN: 0959-8103
    Keywords: anionic copolymerization ; modelling studies ; styrene ; butadiene ; polymerization ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The anionic polymerization of isoprene with n-butyl lithium and polar modifier such as TMEDA and tripiperdinophosphine oxide were studied and kinetic and reactor models are proposed for these systems. Reactor conversion, molecular weight distribution and polymer glass transition temperature had been calculated from the model and compared favorably to the actual data for various combinations of reactor systems and operating conditions. Simulations of the model can be used to design reactor systems and predict polymer properties of large-scale operations from results of small scale batch reactor runs.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pi.1994.210330205
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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