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  • 1990-1994  (2)
  • 1994  (2)
  • 07.20.Dt  (1)
  • CP94  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Potentiation of iron accumulation in cardiac myocytes during the treatment of iron overload in gerbils with the hydroxypyridinone iron chelator CP94 (1994)
    Springer
    BioMetals 7 (1994), S. 267-271 
    Details
    ISSN: 1572-8773
    Keywords: cardiac myocytes ; CP94 ; gerbil ; iron
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Gerbils administered iron dextran are the only animal species which have been shown to develop hemochromatosis of the liver and heart in the same manner as transfusion dependent homozygous thalassemics. The iron chelating hydroxypyridinone, CP94, has been administered prophylactically to iron overloaded gerbils in a dosing regime which favors the formation of bidentate chelated iron, to examine the possibility of additional toxicity being caused to the liver and heart by the bidentate chelated iron complex. Hepatic iron accumulation was inhibited by CP94 administration for up to 6 weeks, but not after 20 weeks. Iron accumulation in the heart was increased significantly after 6 and 20 weeks of chelator treatment. Pathological changes in both organs were markedly more severe after 20 weeks in chelator treated animals. There was a higher incidence of cardiofibrosis and more extensive liver fibrosis in iron overloaded, chelator treated animals after 20 weeks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00144120
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Temperature measurement using degenerate four-wave mixing with non-saturating laser powers (1994)
    Springer
    Applied physics 58 (1994), S. 459-466 
    Details
    ISSN: 1432-0649
    Keywords: 82.40.Py ; 07.20.Dt ; 07.65.-b ; 33.20.Lg
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We report the use of Degenerate Four-Wave Mixing (DFWM) in the OHA 2 Σ + ←X 2 ∏ (υ′ = 0 ←υ″ = 0) band for temperature determination in a propane/air flame using laser powers below the saturation level. We show that at these low power levels the dependence of the signal on the dipole moment for the transition has to be established before meaningful temperature data can be obtained. This presents a paradox in that the temperature has to be known before the form of the dependence on the dipole moment can be determined. Solutions to this paradox are presented. We also show that absorption of the laser beams in this OH band system cannot be neglected and that failure to correctly account for the absorption leads to a large over estimate of the flame temperature. Furthermore, we show that the accuracy of the absorption-corrected temperature is critically dependent on the accuracy with which the measurement position within the flame is known. Finally, the temperature calculated from DFWM spectra using the correct dipole moment power and absorption is compared to the temperatures obtained using Laser-Induced Fluorescence (LIF) and Coherent Anti-Stokes Raman Spectroscopy (CARS).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01081076
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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