ISSN:
0947-6539
Keywords:
chemotaxonomy
;
diterpene metabolites
;
dolabellanes
;
marine natural products
;
oxetanes
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
6,8-Dimethyl-2,7-dioxatricyclo[4.2.13,8]nonan-4β-ol (9aβ) has been prepared from readily accessible starting materials in eight steps (14% overall yield). The parent dioxatricyclic framework 11 was obtained from 1,5-dimethyl-8-oxabicyclo[3.2.1]oct-3-en-6α-ol (7) in six steps (28% yield with respect to 7). Based on the experimental introduction of the oxetane moiety in vitro, a biosynthetic pathway is proposed for dictyoxetane (1) from a known dolabellane metabolite.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19950010607
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