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  • 1995-1999  (184)
  • 1995  (184)
  • Magnetic resonance imaging  (81)
  • Conference proceedings  (52)
  • Rat  (52)
  • 1
    Electronic Resource
    Electronic Resource
    Vacuum rabi splitting in semiconductor microcavities with applied electric and magnetic fields (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 1781-1786 
    Details
    ISSN: 0392-6737
    Keywords: Electron states in low-dimensional structures (including quantum wells, superlattices, layer structures, and intercalation compounds) ; Electroopical effects ; Magnetooptical effects ; Photon interactions with atoms ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary We describe the use of measurements of vacuum Rabi splitting to extract values for the exciton oscillator strengths in In0.13Ga0.87As-GaAs and GaAs-Al0.2Ga0.8As quantum wells. By varying both field and temperature we determine the changes in the oscillator strength in applied electric and magnetic fields. We show that these are in good agreement with the results of quantum well exciton calculations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457280
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  • 2
    Electronic Resource
    Electronic Resource
    Effects of morphine on different aspects of social play in juvenile rats (1995)
    Springer
    Psychopharmacology 117 (1995), S. 225-231 
    Details
    ISSN: 1432-2072
    Keywords: Social play ; Opioid ; Morphine Environment ; Social isolation ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To clarify the influence of opioids on social play, the effects of morphine on playful and non-playful social behavior in juvenile rats was investigated under different conditions. Environmental variables employed were different (dim and intense) levels of illumination during testing, familiarity to the test cage, and different periods of social isolation prior to testing. Under dim light conditions, morphine markedly increased playful social behavior, such as pinning, boxing/wrestling and following/chasing, whereas non-playful social behavior such as social exploration and contact behavior was hardly affected. This effect of morphine was independent of duration of previous isolation and dose-dependent, with a maximal effect at 1.0 mg/kg. The mechanism of this effect is interpreted as an action on the rewarding aspects of play. A dose of 0.1 mg/kg of morphine abolished the initial suppression of play induced by unfamiliarity to the test cage, without influencing total levels of play. This may be an effect of morphine on the integration of sensory stimuli. Under intense light conditions, where playful behavior was completely suppressed, morphine itself hardly affected such behavior, but decreased some aspects of non-playful social behavior. These results suggest that in juvenile rats playful and non-playful forms of social behavior are differentially regulated. In addition, opioid systems may be involved at different levels in the regulation of social play.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02245191
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  • 3
    Electronic Resource
    Electronic Resource
    Cell deletion by apoptosis during regression of rat parotid sialadenosis (1995)
    Springer
    Virchows Archiv 427 (1995), S. 181-186 
    Details
    ISSN: 1432-2307
    Keywords: Isoproterenol ; Apoptosis ; Rat ; Parotid ; Sialadenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Enlargement of the rat parotid salivary glands was induced by repeated administration of isoproterenol. Mean wet weights of the treated glands increased steadily to 240% of control values. Following withdrawal of the drug, quantitative histological techniques were used to investigate the balance between hypertrophy, hyperplasia and apoptosis. The volume occupied by acinar cells relative to the total gland volume together with cytoplasmic|:|nuclear area ratios as measures of hypertrophy increased during the early experimental period. Similarly, serous acinar cell mitotic counts increased, indicating that hyperplasia had occurred. Apoptosis was demonstrated at light microscopical level to be the main mechanism for cell deletion as the glands returned to normal size and weight. The results indicate that hypertrophy and hyperplasia of serous acinar cells contribute to isoproterenol-induced sialadenosis. The experimental animal model demonstrates that these proliferative changes are completed by 48 h and thereafter are balanced by apoptosis as the glands recover their normal size and weight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196524
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  • 4
    Electronic Resource
    Electronic Resource
    Peroxisomes and Hepatotoxicity (1995)
    Springer
    Comparative clinical pathology 5 (1995), S. 189-195 
    Details
    ISSN: 1433-2981
    Keywords: Cell lines ; Guinea pig ; Human ; Hypolipaemic agents ; Peroxisome proliferators ; Rat ; Species difference
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Peroxisomes are ubiquitous organelles of eukaryotic cells and are present in significant amounts in hepatic liver cells. Peroxisomal enzymes contribute to several metabolic pathways including fatty acid, purine and amino acid catabolism or bile acid synthesis. The peroxisomal oxidative reactions produce hydrogen peroxide, mostly degraded by catalase which prevents oxidative stress. Moreover, peroxisomes are involved in arylderivative drug detoxification through its epoxide hydrolase activity. In rodents the exposure of cells to xenobiotic compounds such as fibrates, phthalates/adipates and chlorophenoxyacetic acid derivatives, which are used as hypolipaemic drugs, plasticizers and pesticides respectively, lead to a liver mass increase and to a high peroxisome proliferation. This latter event is due to a strong genetic activation triggered by the PPAR (peroxisome proliferator activated nuclear receptor). Human contrasts with rodent since there is no, or little, effect of the above cited compounds. In contrast, the defect of single or multiple peroxisomal functions caused by genetic disorders lead to an increase of very long chain fatty acid level, which is toxic, especially for brain and kidney. The liver response to xenobiotics of the peroxisome proliferator class may be modulated by auxiliary compounds such as hormones (e.g. thyroid hormone) or nutriments (e.g. retinoids).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00368043
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  • 5
    Electronic Resource
    Electronic Resource
    Excitation energy dependence of the optical properties of InGaAs/GaAs quantum well heterostructures (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 1383-1387 
    Details
    ISSN: 0392-6737
    Keywords: III–V semiconductors ; Electron states in low-dimensional structures (including quantum wells, superlattices, layer structures, and intercalation compounds) ; Excitons and related phenomena (including electron-hole drops) ; III–V compounds and systems ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary We report an experimental study on a large set of InGaAs/GaAs quantum well structures by means of continuous-wave photoluminescence and photoluminescence excitation. The luminescence spectrum at low temperature systematically exhibits a doublet structure whose lineshape is very sensitive to the excitation energy. Accordingly, the excitation spectra detected by monitoring the emission at the two different luminescence peaks have very different profiles, with peaks and/or dips which are not directly related to absorption resonances. As a matter of fact, the anomalies disappear when increasing the temperature or when using an optical bias with energy above the GaAs energy gap. In these cases, the excitation profiles recover the behaviour typical of 2D systems.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457214
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  • 6
    Electronic Resource
    Electronic Resource
    Two-photon absorption spectroscopy in ZnSe/ZnSSe strained-layer superlattices (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 1635-1639 
    Details
    ISSN: 0392-6737
    Keywords: II–VI compounds and other chalcogenides ; Nonlinear optics ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary We report two-photon absorption photoluminescence excitation (TPA-PLE) measurements in ZnSe/ZnSSe strained-layer superlattices (SLS). Polarization-dependent selection rules are observed in TPA spectra depending on the direction of the exciting field with respect to the growth axis of the SLS. Experimental exciton transition energies have found to be in good agreement with theoretical predictions considering strain and confinement effects. Furthermore by means of comparative non-linear technique the TPA coefficient has been measured at different energies and compared with theoretical predictions including quasi-bidimensional excitonic effects. A satisfactory agreement has been shown for the overall spectral behaviour and in some cases also for the TPA coefficient values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457256
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  • 7
    Electronic Resource
    Electronic Resource
    Optical transitions involving excitons in quantum wires (1995)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 1219-1228 
    Details
    ISSN: 0392-6737
    Keywords: Excitons and related phenomena (including electron-hole drops) ; Electron states in low-dimensional structures (including quantum wells, superlattices, layer structures, and intercalation compounds) ; Optical properties of thin films surfaces and layer structures (superlattices, heterojunctions and multilayers) ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary We present a comprehensive discussion of the excitonic properties of V-shaped GaAs and InGaAs quantum wires grown on patterned substrates. Systematic linear and non-linear spectroscopic studies have been performed in order to clarify the impact of lateral confinement on the exciton wave function, namely: enhanced exciton binding energy, localization in magnetic field, recombination from excited states and multiphoton absorption. The careful evaluation of the electron confinement energies, based on the actual quantum wire profile obtained by TEM micrographs, including the internal piezoelectric field induced by off-diagnoal terms of strain tensor, reproduces quite well the measured one-dimensional states. Finally, application of quantum wires in a p-i-n wave guide for bistable operation is demonstrated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02457193
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  • 8
    Electronic Resource
    Electronic Resource
    Repeated administration of a selective dopamine D2 receptor agonist to 6-OHDA — lesioned rats does not affect the survival and outgrowth of intrastriatal fetal mesencephalic grafts (1995)
    Springer
    Experimental brain research 107 (1995), S. 52-58 
    Details
    ISSN: 1432-1106
    Keywords: Transplantation ; Dopamine D2 receptor ; Image analysis ; Tyrosine hydroxylase immunocytochemistry ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of the present study was to investigate the effects of chronic activation of dopamine D2 receptors on the development of grafted fetal rat mesencephalic dopaminergic neurons. Therefore, unilaterally 6-hydroxydopamine — lesioned rats received intrastriatal mesencephalic cell suspension grafts and were subsequently chronically treated with the selective dopamine D2 receptor agonist LY 171555 (Quinpirole). After treatment for 6 consecutive weeks, the rats were processed for tyrosine-hydroxylase immunocytochemistry to assess the survival and outgrowth from grafted dopaminergic neurons. Morphological analysis revealed that, like the volume and morphology of the graft, neither the number nor the cell area of grafted dopaminergic neurons was significantly different between vehicle- and LY 171555-treated animals. To obtain a quantitative estimate of the graft-derived dopaminergic reinnervation, a computerized image analysis system was used. Using this procedure, which was based on the densitometric measurement of tyrosine hydroxylase immunoreactivity in the area adjacent to the grafted tissue, it was found that the extent of graft-derived outgrowth also appeared to be un-affected upon chronic treatment with LY 171555. It is concluded that long-term concurrent administration of a dopamine D2 receptor agonist for 6 consecutive weeks does not impair the survival and outgrowth of grafted rat fetal mesencephalic dopaminergic neurons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00228016
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  • 9
    Electronic Resource
    Electronic Resource
    Leukoencephalopathy with swelling in children and adolescents: MRI patterns and differential diagnosis (1995)
    Springer
    Neuroradiology 37 (1995), S. 679-686 
    Details
    ISSN: 1432-1920
    Keywords: Leukoencephalopathy ; White matter swelling ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In children, several neurological disorders are characterised by spongiform leukoencephalopathy. MRI of the brain typically shows white matter swelling, but does not enable differentiation of the various underlying disorders. The aim of this article is optimisation of the diagnostic value of MRI in leukoencephalopathy accompanied by swelling. MRI-based inclusion criteria were met by 20 patients in our database. The images were analysed using a detailed scoring list. In 13 of the 20 patients the clinical diagnosis was known (11 definite and 2 probable diagnoses). Characteristic MRI abnormalities could be defined in these patients. Of the 7 patients without a diagnosis, 5 had identical MRI abnormalities: difuse hemisphere swelling and typical cysts in frontoparietal subcortical white matter and the tips of the temporal lobes. The clinical picture was also similar in these patients, suggesting a similar disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593394
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  • 10
    Electronic Resource
    Electronic Resource
    Leukoencephalopathy with swelling in children and adolescents: MRI patterns and differential diagnosis (1995)
    Springer
    Neuroradiology 37 (1995), S. 679-686 
    Details
    ISSN: 1432-1920
    Keywords: Key words Leukoencephalopathy ; White matter swelling ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In children, several neurological disorders are characterised by spongiform leukoencephalopathy. MRI of the brain typically shows white matter swelling, but does not enable differentiation of the various underlying disorders. The aim of this article is optimisation of the diagnostic value of MRI in leukoencephalopathy accompanied by swelling. MRI-based inclusion criteria were met by 20 patients in our database. The images were analysed using a detailed scoring list. In 13 of the 20 patients the clinical diagnosis was known (11 definite and 2 probable diagnoses). Characteristic MRI abnormalities could be defined in these patients. Of the 7 patients without a diagnosis, 5 had identical MRI abnormalities: diffuse hemisphere swelling and typical cysts in frontoparietal subcortical white matter and the tips of the temporal lobes. The clinical picture was also similar in these patients, suggesting a similar disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002340050179
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